製品: PPAT Antibody
カタログ: DF12131
タンパク質の説明: Rabbit polyclonal antibody to PPAT
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 50-56kd; 57kD(Calculated).
ユニプロット: Q06203
RRID: AB_2844936

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(91%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(92%), Xenopus(92%)
クローナリティ:
Polyclonal
特異性:
PPAT Antibody detects endogenous levels of total PPAT.
RRID:
AB_2844936
引用形式: Affinity Biosciences Cat# DF12131, RRID:AB_2844936.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Amidophosphoribosyltransferase [Precursor]; Amidophosphoribosyltransferase; ATase; Glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; Glutamine PRPP amidotransferase; GPAT; Phosphoribosyl pyrophosphate amidotransferase; Ppat; PRAT; PUR1_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q06203 PUR1_HUMAN:

Ubiquitously expressed.

タンパク質配列:
MELEELGIREECGVFGCIASGEWPTQLDVPHVITLGLVGLQHRGQESAGIVTSDGSSVPTFKSHKGMGLVNHVFTEDNLKKLYVSNLGIGHTRYATTGKCELENCQPFVVETLHGKIAVAHNGELVNAARLRKKLLRHGIGLSTSSDSEMITQLLAYTPPQEQDDTPDWVARIKNLMKEAPTAYSLLIMHRDVIYAVRDPYGNRPLCIGRLIPVSDINDKEKKTSETEGWVVSSESCSFLSIGARYYREVLPGEIVEISRHNVQTLDIISRSEGNPVAFCIFEYVYFARPDSMFEDQMVYTVRYRCGQQLAIEAPVDADLVSTVPESATPAALAYAGKCGLPYVEVLCKNRYVGRTFIQPNMRLRQLGVAKKFGVLSDNFKGKRIVLVDDSIVRGNTISPIIKLLKESGAKEVHIRVASPPIKYPCFMGINIPTKEELIANKPEFDHLAEYLGANSVVYLSVEGLVSSVQEGIKFKKQKEKKHDIMIQENGNGLECFEKSGHCTACLTGKYPVELEW

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Sheep
100
Dog
100
Rabbit
100
Xenopus
92
Chicken
92
Zebrafish
91
Bovine
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q06203 基板として

Site PTM Type Enzyme
M1 Acetylation
T52 Phosphorylation
K62 Acetylation
K62 Methylation
K62 Ubiquitination
K65 Ubiquitination
K80 Ubiquitination
K81 Acetylation
K81 Ubiquitination
Y94 Phosphorylation
K99 Acetylation
K99 Ubiquitination
R130 Methylation
T166 Phosphorylation
K178 Ubiquitination
K220 Ubiquitination
C339 S-Nitrosylation
C348 S-Nitrosylation
K349 Ubiquitination
T356 Phosphorylation
K371 Acetylation
K372 Acetylation
K372 Ubiquitination
K381 Ubiquitination
K383 Methylation
S399 Phosphorylation
K403 Ubiquitination
K406 Ubiquitination
S408 Phosphorylation
K411 Ubiquitination
K482 Acetylation
K499 Acetylation
K510 Ubiquitination

研究背景

組織特異性:

Ubiquitously expressed.

サブユニット構造:

Homotetramer.

タンパク質ファミリー:

In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.

研究領域

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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