RDH10 Antibody - #DF12105
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製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12105, RRID:AB_2844910.
折りたたみ／展開
RDH 10; RDH10; RDH10_HUMAN; Retinol dehydrogenase 10 (all trans); Retinol dehydrogenase 10; SDR16C4; Short chain dehydrogenase/reductase family 16C member 4;
免疫原
Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.
- Q8IZV5 RDH10_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q8IZV5 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K121 | Ubiquitination | Uniprot | |
| K134 | Ubiquitination | Uniprot | |
| K229 | Ubiquitination | Uniprot | |
| T248 | Phosphorylation | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| K274 | Ubiquitination | Uniprot | |
| Y294 | Phosphorylation | Uniprot | |
| T297 | Phosphorylation | Uniprot | |
| K319 | Ubiquitination | Uniprot | |
| Y322 | Phosphorylation | Uniprot | |
| K338 | Ubiquitination | Uniprot |
研究背景
Retinol dehydrogenase with a clear preference for NADP. Converts all-trans-retinol to all-trans-retinal. Has no detectable activity towards 11-cis-retinol, 9-cis-retinol and 13-cis-retinol.
Microsome membrane>Single-pass membrane protein. Endoplasmic reticulum membrane>Single-pass membrane protein.
Detected in retina, kidney, liver, small intestine, placenta, lung, heart and skeletal muscle.
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
研究領域
· Metabolism > Metabolism of cofactors and vitamins > Retinol metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
参考文献
Application: IF/ICC Species: Human Sample: adipose tissue
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