LMOD3 Antibody - #DF12057
| 製品: | LMOD3 Antibody |
| カタログ: | DF12057 |
| タンパク質の説明: | Rabbit polyclonal antibody to LMOD3 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 65-70 kDa; 65kD(Calculated). |
| ユニプロット: | Q0VAK6 |
| RRID: | AB_2844862 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF12057, RRID:AB_2844862.
折りたたみ／展開
fetal form; Leiomodin; Leiomodin-3; LMOD3; LMOD3_HUMAN;
免疫原
A synthesized peptide derived from human LMOD3, corresponding to a region within the internal amino acids.
Expressed in cardiac and at higher levels in skeletal muscles (at protein level).
- Q0VAK6 LMOD3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSEHSRNSDQEELLDEEINEDEILANLSAEELKELQSEMEVMAPDPSLPVGMIQKDQTDKPPTGNFNHKSLVDYMYWEKASRRMLEEERVPVTFVKSEEKTQEEHEEIEKRNKNMAQYLKEKLNNEIVANKRESKGSSNIQETDEEDEEEEDDDDDDEGEDDGEESEETNREEEGKAKEQIRNCENNCQQVTDKAFKEQRDRPEAQEQSEKKISKLDPKKLALDTSFLKVSTRPSGNQTDLDGSLRRVRKNDPDMKELNLNNIENIPKEMLLDFVNAMKKNKHIKTFSLANVGADENVAFALANMLRENRSITTLNIESNFITGKGIVAIMRCLQFNETLTELRFHNQRHMLGHHAEMEIARLLKANNTLLKMGYHFELPGPRMVVTNLLTRNQDKQRQKRQEEQKQQQLKEQKKLIAMLENGLGLPPGMWELLGGPKPDSRMQEFFQPPPPRPPNPQNVPFSQRSEMMKKPSQAPKYRTDPDSFRVVKLKRIQRKSRMPEAREPPEKTNLKDVIKTLKPVPRNRPPPLVEITPRDQLLNDIRHSSVAYLKPVQLPKELA
研究背景
Essential for the organization of sarcomeric actin thin filaments in skeletal muscle. Increases the rate of actin polymerization.
Ubiquitinated, leading to its degradation. Interaction with KLHL40 negatively regulates ubiquitination and degradation.
Cytoplasm. Cytoplasm>Myofibril>Sarcomere>M line. Cytoplasm>Myofibril>Sarcomere>A band. Cytoplasm>Cytoskeleton.
Note: Highly expressed in nonstriated areas of developing myotubes, where it shows a granular cytoplasmic pattern. In sarcomeres, highly expressed in the M band region and, at lower levels, along actin thin filaments. Not detected in Z-disks. In sarcomeres, may be located near, but not at, actin thin filament pointed end.
Expressed in cardiac and at higher levels in skeletal muscles (at protein level).
Belongs to the tropomodulin family.
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