製品: Phospho-HPD (Thr382) Antibody
カタログ: AF8609
タンパク質の説明: Rabbit polyclonal antibody to Phospho-HPD (Thr382)
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Rabbit
分子量: 45 kDa; 45kD(Calculated).
ユニプロット: P32754
RRID: AB_2843459

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Rabbit(100%)
クローナリティ:
Polyclonal
特異性:
Phospho-HPD (Thr382) Antibody detects endogenous levels of HPD only when phosphorylated at Thr382.
RRID:
AB_2843459
引用形式: Affinity Biosciences Cat# AF8609, RRID:AB_2843459.
コンジュゲート:
Unconjugated.
精製:
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

4 HPPD; 4 hydroxyphenylpyruvate dioxygenase; 4 hydroxyphenylpyruvic acid oxidase; 4-hydroxyphenylpyruvate dioxygenase; 4-hydroxyphenylpyruvic acid oxidase; 4HPPD; GLOD3; glyoxalase domain containing 3; HPD; HPPD_HUMAN; HPPDase; PPD;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MTTYSDKGAKPERGRFLHFHSVTFWVGNAKQAASFYCSKMGFEPLAYRGLETGSREVVSHVIKQGKIVFVLSSALNPWNKEMGDHLVKHGDGVKDIAFEVEDCDYIVQKARERGAKIMREPWVEQDKFGKVKFAVLQTYGDTTHTLVEKMNYIGQFLPGYEAPAFMDPLLPKLPKCSLEMIDHIVGNQPDQEMVSASEWYLKNLQFHRFWSVDDTQVHTEYSSLRSIVVANYEESIKMPINEPAPGKKKSQIQEYVDYNGGAGVQHIALKTEDIITAIRHLRERGLEFLSVPSTYYKQLREKLKTAKIKVKENIDALEELKILVDYDEKGYLLQIFTKPVQDRPTLFLEVIQRHNHQGFGAGNFNSLFKAFEEEQNLRGNLTNMETNGVVPGM

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Pig
0
Horse
0
Bovine
0
Sheep
0
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P32754 基板として

Site PTM Type Enzyme
T2 Acetylation
Y4 Phosphorylation
K63 Ubiquitination
Y105 Phosphorylation
K127 Ubiquitination
S211 Phosphorylation
Y221 Phosphorylation
S222 Phosphorylation
S223 Phosphorylation
S226 Phosphorylation
Y232 Phosphorylation
K247 Acetylation
K249 Ubiquitination
S290 Phosphorylation
Y295 Phosphorylation
Y296 Phosphorylation
K297 Ubiquitination
K311 Ubiquitination
T382 Phosphorylation

研究背景

機能:

Key enzyme in the degradation of tyrosine.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the 4HPPD family.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > Ubiquinone and other terpenoid-quinone biosynthesis.

· Metabolism > Amino acid metabolism > Tyrosine metabolism.

· Metabolism > Amino acid metabolism > Phenylalanine metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.