FBP3 Antibody - #AF9065

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製品: FBP3 Antibody
カタログ: AF9065
タンパク質の説明: Rabbit polyclonal antibody to FBP3
アプリケーション: WB IF/ICC
Cited expt.:
反応性: Human, Mouse
予測: Pig, Horse, Sheep, Dog, Chicken
分子量: 60kDa(Observed); 62kD(Calculated).
ユニプロット: Q96I24
RRID: AB_2843256

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#AF9065-BP

FBP3 Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse
予測:
Pig(100%), Horse(%), Sheep(%), Dog(%), Chicken(%)
クローナリティ:
Polyclonal
特異性:
FBP3 Antibody detects endogenous levels of total FBP3.
RRID:
AB_2843256
引用形式: Affinity Biosciences Cat# AF9065, RRID:AB_2843256.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Far upstream element (FUSE) binding protein 3; Far upstream element binding protein 3; Far upstream element-binding protein 3; FBP3; FLJ25229; FUBP 3; FUBP3; FUBP3_HUMAN; FUSE binding protein 3; FUSE-binding protein 3; OTTHUMP00000022369;

免疫原

免疫原:

A synthesized peptide derived from human FBP3, corresponding to a region within the internal amino acids.

Uniprot:

Q96I24(FUBP3_HUMAN) >>Visit HPA database.

遺伝子(ID):
FUBP3(8939)
発現特異性:
Q96I24 FUBP3_HUMAN:

Detected in a number of cell lines.

タンパク質配列:
MAELVQGQSAPVGMKAEGFVDALHRVRQIAAKIDSIPHLNNSTPLVDPSVYGYGVQKRPLDDGVGNQLGALVHQRTVITEEFKVPDKMVGFIIGRGGEQISRIQAESGCKIQIASESSGIPERPCVLTGTPESIEQAKRLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGISPERAAQVMGPPDRCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNLRRFTIRGVPQQIEVARQLIDEKVGGTNLGAPGAFGQSPFSQPPAPPHQNTFPPRSSGCFPNMAAKVNGNPHSTPVSGPPAFLTQGWGSTYQAWQQPTQQVPSQQSQPQSSQPNYSKAWEDYYKKQSHAASAAPQASSPPDYTMAWAEYYRQQVAFYGQTLGQAQAHSQEQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Chicken
100
Horse
92
Dog
92
Sheep
83
Bovine
75
Xenopus
55
Zebrafish
50
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

May interact with single-stranded DNA from the far-upstream element (FUSE). May activate gene expression.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in a number of cell lines.

参考文献

1). Identification of a key glioblastoma candidate gene, FUBP3, based on weighted gene co-expression network analysis. BMC Neurology, 2022 (PubMed: 35413821) [IF=2.6]

Application: IHC    Species: Human    Sample: GBM tissues

Fig. 4A The expression of FUBP3 in normal tissues adjacent to cancer. B The expression of FUBP3 in GBM tissues. C The expression of CD4 + T cell in GBM tissues. D The expression of CD4 + T cell in normal tissues adjacent to cancer. E The expression of CD8 + T cell in GBM tissues. F The expression of CD8 + T cell in normal tissues adjacent to cancer. G The expression of CD68 + macrophages in GBM tissues. H The expression of CD68 + macrophages in normal tissues adjacent to cancer

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