| 製品: | SLC6A12 Antibody |
| カタログ: | DF9921 |
| タンパク質の説明: | Rabbit polyclonal antibody to SLC6A12 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 69kDa(Observed); 69kD(Calculated). |
| ユニプロット: | P48065 |
| RRID: | AB_2843115 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9921, RRID:AB_2843115.
折りたたみ／展開
Betaine/GABA transporter 1; BGT-1; BGT1; Gamma aminobutyric acid transporter; GAT2; Na(+)/Cl(-) betaine/GABA transporter; S6A12_HUMAN; Slc6a12; Sodium- and chloride-dependent betaine transporter; Solute carrier family 6 (neurotransmitter transporter), member 12; Solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12; Solute carrier family 6 member 12;
免疫原
A synthesized peptide derived from human SLC6A12, corresponding to a region within C-terminal amino acids.
Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
- P48065 S6A12_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDGKVAVQECGPPAVSWVPEEGEKLDQEDEDQVKDRGQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYFIFFFVCGIPVFFLEVALGQYTSQGSVTAWRKICPLFQGIGLASVVIESYLNVYYIIILAWALFYLFSSFTSELPWTTCNNFWNTEHCTDFLNHSGAGTVTPFENFTSPVMEFWERRVLGITSGIHDLGSLRWELALCLLLAWVICYFCIWKGVKSTGKVVYFTATFPYLMLVILLIRGVTLPGAYQGIIYYLKPDLFRLKDPQVWMDAGTQIFFSFAICQGCLTALGSYNKYHNNCYKDCIALCFLNSATSFVAGFVVFSILGFMSQEQGVPISEVAESGPGLAFIAFPKAVTMMPLSQLWSCLFFIMLIFLGLDSQFVCVECLVTASIDMFPRQLRKSGRRELLILTIAVMCYLIGLFLVTEGGMYIFQLFDYYASSGICLLFLSLFEVVCISWVYGADRFYDNIEDMIGYRPWPLVKISWLFLTPGLCLATFLFSLSKYTPLKYNNVYVYPPWGYSIGWFLALSSMVCVPLFVVITLLKTRGPFRKRLRQLITPDSSLPQPKQHPCLDGSAGRNFGPSPTREGLIAGEKETHL
研究背景
Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Membrane>Multi-pass membrane protein.
Liver, heart, skeletal muscle, placenta, and a widespread distribution in the brain.
Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. SLC6A12 subfamily.
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