製品: RABL2B Antibody
カタログ: DF9797
タンパク質の説明: Rabbit polyclonal antibody to RABL2B
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 26 kDa(Observed); 26kD(Calculated).
ユニプロット: Q9UNT1
RRID: AB_2842991

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 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
RABL2B Antibody detects endogenous levels of total RABL2B.
RRID:
AB_2842991
引用形式: Affinity Biosciences Cat# DF9797, RRID:AB_2842991.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ78724; FLJ93981; FLJ98216; MGC117180; OTTHUMP00000045491; OTTHUMP00000045492; OTTHUMP00000045493; OTTHUMP00000203788; OTTHUMP00000203792; RAB like 2B; RAB like protein 2B; RAB member of RAS oncogene family like 2B; Rab-like protein 2A; RABL2A; RABL2B; RBL2A_HUMAN; RP11-395L14.2;

免疫原

免疫原:

A synthesized peptide derived from human RABL2B, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9UNT1 RBL2B_HUMAN:

Expressed in the testis.

タンパク質配列:
MAEDKTKPSELDQGKYDADDNVKIICLGDSAVGKSKLMERFLMDGFQPQQLSTYALTLYKHTATVDGRTILVDFWDTAGQERFQSMHASYYHKAHACIMVFDVQRKVTYRNLSTWYTELREFRPEIPCIVVANKIDDINVTQKSFNFAKKFSLPLYFVSAADGTNVVKLFNDAIRLAVSYKQNSQDFMDEIFQELENFSLEQEEEDVPDQEQSSSIETPSEEAASPHS

研究背景

機能:

Small GTPase required for ciliation. Activated in a guanine nucleotide exchange factor (GEF)-independent manner via its intrinsic GDP for GTP nucleotide exchange ability. Involved in ciliary assembly by binding the intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia.

細胞の位置付け:

Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome>Centriole. Cytoplasm>Cytoskeleton>Cilium basal body. Cytoplasm.
Note: Localizes on the mother centriole. Localizes slightly apical to the subdistal appendage, but below the distal appendage.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in the testis.

タンパク質ファミリー:

Belongs to the small GTPase superfamily. Rab family.

Restrictive clause

 

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