製品: PIGP Antibody
カタログ: DF9744
タンパク質の説明: Rabbit polyclonal antibody to PIGP
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Monkey
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 18 kDa; 18kD(Calculated).
ユニプロット: P57054
RRID: AB_2842939

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Monkey
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%)
クローナリティ:
Polyclonal
特異性:
PIGP Antibody detects endogenous levels of total PIGP.
RRID:
AB_2842939
引用形式: Affinity Biosciences Cat# DF9744, RRID:AB_2842939.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

DCRC; DCRC S; Down syndrome critical region gene 5; Down syndrome critical region protein 5; Down syndrome critical region protein C; DSCR 5; DSCR5; DSCRC; DSRC; Phosphatidylinositol glycan anchor biosynthesis class P; Phosphatidylinositol glycan biosynthesis class P; Phosphatidylinositol glycan biosynthesis class P protein; Phosphatidylinositol glycan class P; Phosphatidylinositol n acetylglucosaminyltranferase subunit; Phosphatidylinositol N acetylglucosaminyltransferase subunit P; Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Phosphatidylinositol-glycan biosynthesis class P protein; PIG-P; PIGP; PIGP_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P57054 PIGP_HUMAN:

Ubiquitous.

タンパク質配列:
MVPRSTSLTLIVFLFHRLSKAPGKMVENSPSPLPERAIYGFVLFLSSQFGFILYLVWAFIPESWLNSLGLTYWPQKYWAVALPVYLLIAIVIGYVLLFGINMMSTSPLDSIHTITDNYAKNQQQKKYQEEAIPALRDISISEVNQMFFLAAKELYTKN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
78
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P57054 基板として

Site PTM Type Enzyme
T6 Phosphorylation
T9 Phosphorylation
S19 Phosphorylation
K126 Ubiquitination
K157 Ubiquitination

研究背景

機能:

Part of the complex catalyzing the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Associates with PIGA, PIGC, PIGH, PIGQ and DPM2. The latter is not essential for activity.

タンパク質ファミリー:

Belongs to the PIGP family.

研究領域

· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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For Research Use Only.
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