PIGA Antibody - #DF9742
| 製品: | PIGA Antibody |
| カタログ: | DF9742 |
| タンパク質の説明: | Rabbit polyclonal antibody to PIGA |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat, Monkey |
| 分子量: | 54 kDa; 54kD(Calculated). |
| ユニプロット: | P37287 |
| RRID: | AB_2842937 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9742, RRID:AB_2842937.
折りたたみ／展開
Class A GlcNAc inositol phospholipid assembly protein; GlcNAc PI synthesis protein; GlcNAc-PI synthesis protein; GPI3; MCAHS2; Phosphatidylinositol glycan anchor biosynthesis class A; Phosphatidylinositol glycan biosynthesis class A protein; Phosphatidylinositol N-acetylglucosaminyltransferase subunit A; Phosphatidylinositol-glycan biosynthesis class A protein; PIG A; PIG-A; Piga; PIGA_HUMAN;
免疫原
- P37287 PIGA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MACRGGAGNGHRASATLSRVSPGSLYTCRTRTHNICMVSDFFYPNMGGVESHIYQLSQCLIERGHKVIIVTHAYGNRKGIRYLTSGLKVYYLPLKVMYNQSTATTLFHSLPLLRYIFVRERVTIIHSHSSFSAMAHDALFHAKTMGLQTVFTDHSLFGFADVSSVLTNKLLTVSLCDTNHIICVSYTSKENTVLRAALNPEIVSVIPNAVDPTDFTPDPFRRHDSITIVVVSRLVYRKGIDLLSGIIPELCQKYPDLNFIIGGEGPKRIILEEVRERYQLHDRVRLLGALEHKDVRNVLVQGHIFLNTSLTEAFCMAIVEAASCGLQVVSTRVGGIPEVLPENLIILCEPSVKSLCEGLEKAIFQLKSGTLPAPENIHNIVKTFYTWRNVAERTEKVYDRVSVEAVLPMDKRLDRLISHCGPVTGYIFALLAVFNFLFLIFLRWMTPDSIIDVAIDATGPRGAWTNNYSHSKRGGENNEISETR
PTMs - P37287 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| R4 | Methylation | Uniprot | |
| S21 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| T27 | Phosphorylation | Uniprot | |
| T32 | Phosphorylation | Uniprot | |
| Y254 | Phosphorylation | Uniprot | |
| K293 | Ubiquitination | Uniprot | |
| S354 | Phosphorylation | Uniprot | |
| K361 | Ubiquitination | Uniprot | |
| K367 | Ubiquitination | Uniprot | |
| Y385 | Phosphorylation | Uniprot | |
| K396 | Acetylation | Uniprot |
研究背景
Necessary for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, the very early intermediate in GPI-anchor biosynthesis.
Endoplasmic reticulum membrane>Single-pass membrane protein.
Associates with PIGC, PIGH, PIGP, PIGQ and DPM2. The latter is not essential for activity. Interacts directly with PIGY.
Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Glycosylphosphatidylinositol (GPI)-anchor biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
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