製品: PEX11A Antibody
カタログ: DF9734
タンパク質の説明: Rabbit polyclonal antibody to PEX11A
アプリケーション: WB
反応性: Human, Mouse, Rat
予測: Bovine, Sheep, Dog
分子量: 28 kDa; 28kD(Calculated).
ユニプロット: O75192
RRID: AB_2842929

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Bovine(80%), Sheep(90%), Dog(80%)
クローナリティ:
Polyclonal
特異性:
PEX11A Antibody detects endogenous levels of total PEX11A.
RRID:
AB_2842929
引用形式: Affinity Biosciences Cat# DF9734, RRID:AB_2842929.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

28 kDa peroxisomal integral membrane protein; HsPEX11p; MGC119947; MGC138534; Peroxin-11A; Peroxisomal biogenesis factor 11 alpha; Peroxisomal biogenesis factor 11A; Peroxisomal membrane protein 11A; PEX11-alpha; PEX11A; PMP28; Protein PEX11 homolog alpha; PX11A_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MDAFTRFTNQTQGRDRLFRATQYTCMLLRYLLEPKAGKEKVVMKLKKLESSVSTGRKWFRLGNVVHAIQATEQSIHATDLVPRLCLTLANLNRVIYFICDTILWVRSVGLTSGINKEKWRTRAAHHYYYSLLLSLVRDLYEISLQMKRVTCDRAKKEKSASQDPLWFSVAEEETEWLQSFLLLLFRSLKQHPPLLLDTVKNLCDILNPLDQLGIYKSNPGIIGLGGLVSSIAGMITVAYPQMKLKTR

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Sheep
90
Bovine
80
Dog
80
Pig
70
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O75192 基板として

Site PTM Type Enzyme
Y23 Phosphorylation
K47 Ubiquitination
K118 Acetylation
Y127 Phosphorylation
Y128 Phosphorylation
Y129 Phosphorylation

研究背景

機能:

May be involved in peroxisomal proliferation and may regulate peroxisomes division. May mediate binding of coatomer proteins to the peroxisomal membrane (By similarity). Promotes membrane protrusion and elongation on the peroxisomal surface.

PTMs:

Seems not to be N-glycosylated.

細胞の位置付け:

Peroxisome membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Homodimer. Heterodimer with PEX11G. Probably interacts with COPB2 and COPA (By similarity). Interacts with PEX19. Interacts with FIS1.

タンパク質ファミリー:

Belongs to the peroxin-11 family.

研究領域

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

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