NDUFA1 Antibody - #DF9659
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| 製品: | NDUFA1 Antibody |
| カタログ: | DF9659 |
| タンパク質の説明: | Rabbit polyclonal antibody to NDUFA1 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Chicken, Xenopus |
| 分子量: | 8 kDa; 8kD(Calculated). |
| ユニプロット: | O15239 |
| RRID: | AB_2842855 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9659, RRID:AB_2842855.
折りたたみ／展開
CI MWFE; CI-MWFE; Complex I MWFE; complex I MWFE subunit; Complex I-MWFE; MWFE; MWFE, B. taurus, homolog of; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1 7.5kDa; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 1; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1; NADH oxidoreductase subunit MWFE; NADH ubiquinone oxidoreductase (complex 1); NADH ubiquinone oxidoreductase MWFE subunit; NADH-ubiquinone oxidoreductase 1 alpha subcomplex, 1; NADH-ubiquinone oxidoreductase MWFE subunit; NDUA1_HUMAN; NDUFA 1; NDUFA1; Type I dehydrogenase; ZNF 183; ZNF183;
免疫原
- O15239 NDUA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MWFEILPGLSVMGVCLLIPGLATAYIHRFTNGGKEKRVAHFGYHWSLMERDRRISGVDRYYVSKGLENID
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15239 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S55 | Phosphorylation | Uniprot | |
| R59 | Methylation | Uniprot | |
| Y60 | Phosphorylation | Uniprot | |
| Y61 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| K64 | Ubiquitination | Uniprot |
研究背景
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Mitochondrion inner membrane>Single-pass membrane protein>Matrix side.
Primarily expressed in heart and skeletal muscle.
Complex I is composed of 45 different subunits.
Belongs to the complex I NDUFA1 subunit family.
研究領域
· Human Diseases > Endocrine and metabolic diseases > Non-alcoholic fatty liver disease (NAFLD).
· Human Diseases > Neurodegenerative diseases > Alzheimer's disease.
· Human Diseases > Neurodegenerative diseases > Parkinson's disease.
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
· Metabolism > Energy metabolism > Oxidative phosphorylation.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Nervous system > Retrograde endocannabinoid signaling. (View pathway)
参考文献
Application: WB Species: human Sample: Liver
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