MOT11 Antibody - #DF9632

(2)  
製品: MOT11 Antibody
カタログ: DF9632
タンパク質の説明: Rabbit polyclonal antibody to MOT11
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 48 kDa; 48kD(Calculated).
ユニプロット: Q8NCK7
RRID: AB_2842828

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
MOT11 Antibody detects endogenous levels of total MOT11.
RRID:
AB_2842828
引用形式: Affinity Biosciences Cat# DF9632, RRID:AB_2842828.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

FLJ90193; MCT 11; Monocarboxylate transporter 11; MOT11_HUMAN; SLC16A11; Solute carrier family 16 member 11 (monocarboxylic acid transporter 11); Solute carrier family 16 member 11;

免疫原

免疫原:

A synthesized peptide derived from human MOT11, corresponding to a region within N-terminal amino acids.

Uniprot:

Q8NCK7(MOT11_HUMAN) >>Visit HPA database.

遺伝子(ID):
SLC16A11(162515)
発現特異性:
Q8NCK7 MOT11_HUMAN:

Expressed in liver, salivary gland and thyroid.

タンパク質配列:
MPAPQRKHRRGGFSHRCFPTPQTAMTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC

研究背景

機能:

Proton-linked monocarboxylate transporter. It catalyzes the transport of pyruvate across the plasma membrane. Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids.

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein. Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in liver, salivary gland and thyroid.

タンパク質ファミリー:

Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.

Restrictive clause

 

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