製品: IMMP2L Antibody
カタログ: DF9630
タンパク質の説明: Rabbit polyclonal antibody to IMMP2L
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Zebrafish, Bovine, Horse, Xenopus
分子量: 20 kDa; 20kD(Calculated).
ユニプロット: Q96T52
RRID: AB_2842826

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Zebrafish(91%), Bovine(100%), Horse(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
IMMP2L Antibody detects endogenous levels of total IMMP2L.
RRID:
AB_2842826
引用形式: Affinity Biosciences Cat# DF9630, RRID:AB_2842826.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

EC 3.4.21; IMP2; IMP2 inner mitochondrial membrane peptidase like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like (S. cerevisiae); IMP2 inner mitochondrial membrane protease like; IMP2 like; IMP2 like protein; IMP2-LIKE; Inner mitochondrial membrane peptidase 2 like; Mitochondrial inner membrane protease subunit 2; OTTHUMP00000207168; OTTHUMP00000207189;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q96T52 IMP2L_HUMAN:

Expressed in all tissues tested except adult liver and lung.

タンパク質配列:
MAQSQGWVKRYIKAFCKGFFVAVPVAVTFLDRVACVARVEGASMQPSLNPGGSQSSDVVLLNHWKVRNFEVHRGDIVSLVSPKNPEQKIIKRVIALEGDIVRTIGHKNRYVKVPRGHIWVEGDHHGHSFDSNSFGPVSLGLLHAHATHILWPPERWQKLESVLPPERLPVQREEE

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Bovine
100
Xenopus
100
Zebrafish
91
Pig
0
Sheep
0
Dog
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96T52 基板として

Site PTM Type Enzyme
S43 Phosphorylation
S47 Phosphorylation
K83 Ubiquitination
K88 Ubiquitination
K112 Methylation

研究背景

機能:

Catalyzes the removal of transit peptides required for the targeting of proteins from the mitochondrial matrix, across the inner membrane, into the inter-membrane space. Known to process the nuclear encoded protein DIABLO.

細胞の位置付け:

Mitochondrion inner membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in all tissues tested except adult liver and lung.

サブユニット構造:

Heterodimer of 2 subunits, IMMPL1 and IMMPL2.

タンパク質ファミリー:

Belongs to the peptidase S26 family. IMP2 subfamily.

研究領域

· Genetic Information Processing > Folding, sorting and degradation > Protein export.

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