MARCH9 Antibody - #DF9485
| 製品: | MARCH9 Antibody |
| カタログ: | DF9485 |
| タンパク質の説明: | Rabbit polyclonal antibody to MARCH9 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 予測: | Pig |
| 分子量: | 38 kDa; 38kD(Calculated). |
| ユニプロット: | Q86YJ5 |
| RRID: | AB_2842681 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9485, RRID:AB_2842681.
折りたたみ／展開
BC019560; E3 ubiquitin protein ligase MARCH9; FLJ36578; MARCH IX; Membrane associated RING CH protein IX; membrane associated ring finger (C3HC4) 9; Membrane associated RING finger protein 9; RING finger protein 179; RNF179;
免疫原
A synthesized peptide derived from human MARCH9, corresponding to a region within N-terminal amino acids.
- Q86YJ5 MARH9_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLKSRLRMFLNELKLLVLTGGGRPRAEPQPRGGRGGGCGWAPFAGCSTRDGDGDEEEYYGSEPRARGLAGDKEPRAGPLPPPAPPLPPPGALDALSLSSSLDSGLRTPQCRICFQGPEQGELLSPCRCDGSVRCTHQPCLIRWISERGSWSCELCYFKYQVLAISTKNPLQWQAISLTVIEKVQIAAIVLGSLFLVASISWLIWSSLSPSAKWQRQDLLFQICYGMYGFMDVVCIGLIIHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDIGGDAGGGTAGKSGPRNSRTGPTSGATSRPPAAQRMRTLLPQRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I, CD4 and ICAM1, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Golgi apparatus membrane>Multi-pass membrane protein. Lysosome membrane>Multi-pass membrane protein.
Ubiquitously expressed.
The RING-CH-type zinc finger domain is required for E3 ligase activity.
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