製品: DHRS10 Antibody
カタログ: DF9435
タンパク質の説明: Rabbit polyclonal antibody to DHRS10
アプリケーション: WB
反応性: Human, Mouse
分子量: 28 kDa, 20 kDa(Observed); 28kD(Calculated).
ユニプロット: Q9BPX1
RRID: AB_2842631

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
DHRS10 Antibody detects endogenous levels of total DHRS10.
RRID:
AB_2842631
引用形式: Affinity Biosciences Cat# DF9435, RRID:AB_2842631.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

17 beta HSD 14; 17 beta hydroxysteroid dehydrogenase 14; 17 beta hydroxysteroid dehydrogenase DHRS10; Dehydrogenase/reductase (SDR family) member 10; Dehydrogenase/reductase SDR family member 10; DHRS10; Hydroxysteroid (17 beta) dehydrogenase 14; Retinal short chain dehydrogenase/reductase 3; Retinal short chain dehydrogenase/reductase retSDR3; retSDR3; SDR3; SDR47C1; Short chain dehydrogenase/reductase family 47C, member 1;

免疫原

免疫原:

A synthesized peptide derived from human DHRS10, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9BPX1 DHB14_HUMAN:

Highly expressed in brain, placenta, liver and kidney.

タンパク質配列:
MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPGAVFILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASEANFCTGIELLVTGGAELGYGCKASRSTPVDAPDIPS

研究背景

機能:

Has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity. Converts oestradiol to oestrone. The physiological substrate is not known. Acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro).

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in brain, placenta, liver and kidney.

タンパク質ファミリー:

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.