NT5C2 Antibody - #DF9431
| 製品: | NT5C2 Antibody |
| カタログ: | DF9431 |
| タンパク質の説明: | Rabbit polyclonal antibody to NT5C2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Monkey |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 65 kDa; 65kD(Calculated). |
| ユニプロット: | P49902 |
| RRID: | AB_2842627 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9431, RRID:AB_2842627.
折りたたみ／展開
5' nucleotidase (purine) cytosolic type B; 5NTC_HUMAN; cN II; Cytosolic 5''-nucleotidase II; Cytosolic IMP/GMP-specific 5'-nucleotidase; Cytosolic purine 5' nucleotidase; Cytosolic purine 5''-nucleotidase; GMP; NT5B; nt5c2; NT5CP; NUCLEOTIDASE, 5-PRIME, CYTOSOLIC II; NUCLEOTIDASE, 5-PRIME, TYPE B; PNT5; PURINE 5-PRIME-NUCLEOTIDASE;
免疫原
- P49902 5NTC_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSTSWSDRLQNAADMPANMDKHALKKYRREAYHRVFVNRSLAMEKIKCFGFDMDYTLAVYKSPEYESLGFELTVERLVSIGYPQELLSFAYDSTFPTRGLVFDTLYGNLLKVDAYGNLLVCAHGFNFIRGPETREQYPNKFIQRDDTERFYILNTLFNLPETYLLACLVDFFTNCPRYTSCETGFKDGDLFMSYRSMFQDVRDAVDWVHYKGSLKEKTVENLEKYVVKDGKLPLLLSRMKEVGKVFLATNSDYKYTDKIMTYLFDFPHGPKPGSSHRPWQSYFDLILVDARKPLFFGEGTVLRQVDTKTGKLKIGTYTGPLQHGIVYSGGSSDTICDLLGAKGKDILYIGDHIFGDILKSKKRQGWRTFLVIPELAQELHVWTDKSSLFEELQSLDIFLAELYKHLDSSSNERPDISSIQRRIKKVTHDMDMCYGMMGSLFRSGSRQTLFASQVMRYADLYAASFINLLYYPFSYLFRAAHVLMPHESTVEHTHVDINEMESPLATRNRTSVDFKDTDYKRHQLTRSISEIKPPNLFPLAPQEITHCHDEDDDEEEEEEEE
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P49902 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T3 | Phosphorylation | Uniprot | |
| S4 | Phosphorylation | Uniprot | |
| K21 | Ubiquitination | Uniprot | |
| K26 | Acetylation | Uniprot | |
| Y32 | Phosphorylation | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| Y178 | Phosphorylation | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| S193 | Phosphorylation | Uniprot | |
| K211 | Ubiquitination | Uniprot | |
| K217 | Ubiquitination | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K231 | Ubiquitination | Uniprot | |
| S237 | Phosphorylation | Uniprot | |
| K244 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K292 | Ubiquitination | Uniprot | |
| K313 | Ubiquitination | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| K359 | Ubiquitination | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S418 | Phosphorylation | Uniprot | |
| T427 | Phosphorylation | Uniprot | |
| S439 | Phosphorylation | Uniprot | |
| S502 | Phosphorylation | Uniprot | |
| T510 | Phosphorylation | Uniprot | |
| S511 | Phosphorylation | Uniprot | |
| K515 | Ubiquitination | Uniprot | |
| Y519 | Phosphorylation | Uniprot | |
| K520 | Ubiquitination | Uniprot | |
| S527 | Phosphorylation | Uniprot | |
| S529 | Phosphorylation | Uniprot | |
| K532 | Ubiquitination | Uniprot |
研究背景
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
Cytoplasm.
Homotetramer.
Belongs to the 5'(3')-deoxyribonucleotidase family.
研究領域
· Metabolism > Nucleotide metabolism > Purine metabolism.
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Metabolism of cofactors and vitamins > Nicotinate and nicotinamide metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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