| 製品: | CABYR Antibody |
| カタログ: | DF9310 |
| タンパク質の説明: | Rabbit polyclonal antibody to CABYR |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 53kDa(Observed); 53kD(Calculated). |
| ユニプロット: | O75952 |
| RRID: | AB_2842506 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF9310, RRID:AB_2842506.
折りたたみ／展開
CABYR; CABYR_HUMAN; Calcium binding tyrosine-(Y)-phosphorylation regulated; Calcium-binding protein 86; Calcium-binding tyrosine phosphorylation-regulated protein; Cancer/testis antigen 88; CBP86; CT88; Fibrousheathin II; Fibrousheathin-2; FSP-2; FSP2; Testis-specific calcium-binding protein CBP86;
免疫原
A synthesized peptide derived from human CABYR, corresponding to a region within the internal amino acids.
Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors.
- O75952 CABYR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MISSKPRLVVPYGLKTLLEGISRAVLKTNPSNINQFAAAYFQELTMYRGNTTMDIKDLVKQFHQIKVEKWSEGTTPQKKLECLKEPGKTSVESKVPTQMEKSTDTDEDNVTRTEYSDKTTQFPSVYAVPGTEQTEAVGGLSSKPATPKTTTPPSSPPPTAVSPEFAYVPADPAQLAAQMLGKVSSIHSDQSDVLMVDVATSMPVVIKEVPSSEAAEDVMVAAPLVCSGKVLEVQVVNQTSVHVDLGSQPKENEAEPSTASSVPLQDEQEPPAYDQAPEVTLQADIEVMSTVHISSVYNDVPVTEGVVYIEQLPEQIVIPFTDQVACLKENEQSKENEQSPRVSPKSVVEKTTSGMSKKSVESVKLAQLEENAKYSSVYMEAEATALLSDTSLKGQPEVPAQLLDAEGAIKIGSEKSLHLEVEITSIVSDNTGQEESGENSVPQEMEGKPVLSGEAAEAVHSGTSVKSSSGPFPPAPEGLTAPEIEPEGESTAE
研究背景
May function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction. Isoform 1 binds calcium in vitro. Isoform 2 and isoform 6 probably bind calcium. Isoform 3 and isoform 5 do not bind calcium in vitro. Isoform 4 probably does not bind calcium.
Isoform 1 is phosphorylated on tyrosine residues during in vitro capacitation. Isoform 3 and isoform 5 are phosphorylated by GSK3B in vitro. Dephosphorylation affects its ability to bind calcium.
Cytoplasm>Cytoskeleton. Cell projection>Cilium>Flagellum.
Note: Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella.
Nucleus. Cytoplasm. Cell projection>Cilium>Flagellum.
Note: According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.
Nucleus. Cytoplasm. Cell projection>Cilium>Flagellum.
Note: According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.
Nucleus. Cytoplasm. Cell projection>Cilium>Flagellum.
Note: According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.
Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors.
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