製品: B4GALT2 Antibody
カタログ: DF9273
タンパク質の説明: Rabbit polyclonal antibody to B4GALT2
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 42 kDa; 42kD(Calculated).
ユニプロット: O60909
RRID: AB_2842469

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Zebrafish(86%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(88%), Chicken(86%), Xenopus(86%)
クローナリティ:
Polyclonal
特異性:
B4GALT2 Antibody detects endogenous levels of total B4GALT2.
RRID:
AB_2842469
引用形式: Affinity Biosciences Cat# DF9273, RRID:AB_2842469.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

4-galactosyltransferase 2; 4-galactosyltransferase; 4-GalTase 2; B4Gal T2; b4Gal-T2; B4GALT2; B4GT2_HUMAN; Beta 1,4 galactosyltransferase 2; Beta 1,4 GalTase 2; Beta 4 GalT2; Beta N acetylglucosaminyl glycolipid beta 1,4 galactosyltransferase 2; Beta-1; Beta-N-acetylglucosaminyl-glycolipid beta-1; Beta4Gal T2; Beta4Gal-T2; Nal synthase; UDP Gal:beta GlcNAc beta 1,4 galactosyltransferase 2; UDP Gal:betaGlcNAc beta 1,4 galactosyltransferase polypeptide 2; UDP galactose:beta N acetylglucosamine beta 1,4 galactosyltransferase 2; UDP-Gal:beta-GlcNAc beta-1; UDP-galactose:beta-N-acetylglucosamine beta-1;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
O60909 B4GT2_HUMAN:

Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain.

タンパク質配列:
MSRLLGGTLERVCKAVLLLCLLHFLVAVILYFDVYAQHLAFFSRFSARGPAHALHPAASSSSSSSNCSRPNATASSSGLPEVPSALPGPTAPTLPPCPDSPPGLVGRLLIEFTSPMPLERVQRENPGVLMGGRYTPPDCTPAQTVAVIIPFRHREHHLRYWLHYLHPILRRQRLRYGVYVINQHGEDTFNRAKLLNVGFLEALKEDAAYDCFIFSDVDLVPMDDRNLYRCGDQPRHFAIAMDKFGFRLPYAGYFGGVSGLSKAQFLRINGFPNEYWGWGGEDDDIFNRISLTGMKISRPDIRIGRYRMIKHDRDKHNEPNPQRFTKIQNTKLTMKRDGIGSVRYQVLEVSRQPLFTNITVDIGRPPSWPPRG

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Rabbit
100
Dog
88
Xenopus
86
Zebrafish
86
Chicken
86
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O60909 基板として

Site PTM Type Enzyme
Y134 Phosphorylation
Y344 Phosphorylation
S350 Phosphorylation

研究背景

機能:

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Can produce lactose.

細胞の位置付け:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.
Note: Trans cisternae of Golgi stack.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Weakly expressed in various tissues. Highest expression in prostate, testis, ovary, intestine, muscle, and in fetal brain.

タンパク質ファミリー:

Belongs to the glycosyltransferase 7 family.

研究領域

· Metabolism > Carbohydrate metabolism > Galactose metabolism.

· Metabolism > Glycan biosynthesis and metabolism > N-Glycan biosynthesis.

· Metabolism > Glycan biosynthesis and metabolism > Other types of O-glycan biosynthesis.

· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - keratan sulfate.

· Metabolism > Glycan biosynthesis and metabolism > Glycosphingolipid biosynthesis - lacto and neolacto series.

· Metabolism > Global and overview maps > Metabolic pathways.

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