製品: B3GALT6 Antibody
カタログ: DF9271
タンパク質の説明: Rabbit polyclonal antibody to B3GALT6
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken, Xenopus
分子量: 37 kDa,50kDa; 37kD(Calculated).
ユニプロット: Q96L58
RRID: AB_2842467

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(90%), Zebrafish(90%), Bovine(90%), Horse(90%), Sheep(90%), Dog(90%), Chicken(90%), Xenopus(90%)
クローナリティ:
Polyclonal
特異性:
B3GALT6 Antibody detects endogenous levels of total B3GALT6.
RRID:
AB_2842467
引用形式: Affinity Biosciences Cat# DF9271, RRID:AB_2842467.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Beta 1 3 galactosyltransferase 6; Beta 3GalT6; Beta3GalT6; GAG GalTII; Galactosyltransferase II; Galactosylxylosylprotein 3 beta galactosyltransferase; UDP Gal:betaGal beta 1 3 galactosyltransferase polypeptide 6; UDP Gal:betaGlcNAc beta 1 3 galactosyltransferase polypeptide 6;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q96L58 B3GT6_HUMAN:

Ubiquitous.

タンパク質配列:
MKLLRRAWRRRAALGLGTLALCGAALLYLARCAAEPGDPRAMSGRSPPPPAPARAAAFLAVLVASAPRAAERRSVIRSTWLARRGAPGDVWARFAVGTAGLGAEERRALEREQARHGDLLLLPALRDAYENLTAKVLAMLAWLDEHVAFEFVLKADDDSFARLDALLAELRAREPARRRRLYWGFFSGRGRVKPGGRWREAAWQLCDYYLPYALGGGYVLSADLVHYLRLSRDYLRAWHSEDVSLGAWLAPVDVQREHDPRFDTEYRSRGCSNQYLVTHKQSLEDMLEKHATLAREGRLCKREVQLRLSYVYDWSAPPSQCCQRREGIP

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
90
Horse
90
Bovine
90
Sheep
90
Dog
90
Xenopus
90
Zebrafish
90
Chicken
90
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96L58 基板として

Site PTM Type Enzyme
S65 Phosphorylation
Y129 Phosphorylation
T133 Phosphorylation
K280 Ubiquitination
S282 Phosphorylation
K289 Ubiquitination

研究背景

機能:

Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Has a preference for galactose-beta-1,4-xylose that is found in the linker region of glycosaminoglycans, such as heparan sulfate and chondroitin sulfate. Has no activity towards substrates with terminal glucosamine or galactosamine residues.

細胞の位置付け:

Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

タンパク質ファミリー:

Belongs to the glycosyltransferase 31 family.

研究領域

· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate.

· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - heparan sulfate / heparin.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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For Research Use Only.
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