製品: BCL2L14 Antibody
カタログ: DF9220
タンパク質の説明: Rabbit polyclonal antibody to BCL2L14
アプリケーション: WB IHC
反応性: Human, Mouse
予測: Bovine, Sheep
分子量: 37 kDa(Observed); 37kD(Calculated).
ユニプロット: Q9BZR8
RRID: AB_2842416

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Bovine(83%), Sheep(83%)
クローナリティ:
Polyclonal
特異性:
BCL2L14 Antibody detects endogenous levels of total BCL2L14.
RRID:
AB_2842416
引用形式: Affinity Biosciences Cat# DF9220, RRID:AB_2842416.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Apoptosis facilitator Bcl 2 like protein 14; Apoptosis regulator BCL G; Bcl2 L 14; BCL2 like 14 (apoptosis facilitator); BCL2 like 14; BCL2L14; BCLG; testicular tissue protein Li 26;

免疫原

免疫原:

A synthesized peptide derived from human BCL2L14, corresponding to a region within N-terminal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9BZR8 B2L14_HUMAN:

Isoform 1 is widely expressed. Isoform 2 is testis-specific.

タンパク質配列:
MCSTSGCDLEEIPLDDDDLNTIEFKILAYYTRHHVFKSTPALFSPKLLRTRSLSQRGLGNCSANESWTEVSWPCRNSQSSEKAINLGKKKSSWKAFFGVVEKEDSQSTPAKVSAQGQRTLEYQDSHSQQWSRCLSNVEQCLEHEAVDPKVISIANRVAEIVYSWPPPQATQAGGFKSKEIFVTEGLSFQLQGHVPVASSSKKDEEEQILAKIVELLKYSGDQLERKLKKDKALMGHFQDGLSYSVFKTITDQVLMGVDPRGESEVKAQGFKAALVIDVTAKLTAIDNHPMNRVLGFGTKYLKENFSPWIQQHGGWEKILGISHEEVD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
83
Sheep
83
Rabbit
71
Pig
67
Horse
55
Dog
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Plays a role in apoptosis.

PTMs:

Phosphorylated by MELK, leading to inhibit its pro-apoptotic function.

細胞の位置付け:

Cytoplasm.

Cytoplasm>Cytosol.
Note: Diffusely distributed throughout the cytosol.

Endomembrane system.
Note: Predominantly localized to cytosolic organelles.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Isoform 1 is widely expressed. Isoform 2 is testis-specific.

タンパク質ファミリー:

Belongs to the Bcl-2 family.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.