製品: GPT2 Antibody
カタログ: DF9183
タンパク質の説明: Rabbit polyclonal antibody to GPT2
アプリケーション: WB IF/ICC
反応性: Human
予測: Bovine, Horse, Sheep, Dog
分子量: 58 kDa; 58kD(Calculated).
ユニプロット: Q8TD30
RRID: AB_2842379

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Bovine(89%), Horse(89%), Sheep(89%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
GPT2 Antibody detects endogenous levels of total GPT2.
RRID:
AB_2842379
引用形式: Affinity Biosciences Cat# DF9183, RRID:AB_2842379.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

AAT2; Alanine aminotransferase 2; ALAT2_HUMAN; ALT2; Glutamate pyruvate transaminase 2; Glutamic alanine transaminase 2; Glutamic pyruvate transaminase (alanine aminotransferase) 2; Glutamic pyruvic transaminase 2; Glutamic--alanine transaminase 2; Glutamic--pyruvic transaminase 2; GPT 2; gpt2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q8TD30 ALAT2_HUMAN:

Expressed at high levels in muscle, adipose tissue, kidney and brain and at lower levels in the liver and breast.

タンパク質配列:
MQRAAALVRRGCGPRTPSSWGRSQSSAAAEASAVLKVRPERSRRERILTLESMNPQVKAVEYAVRGPIVLKAGEIELELQRGIKKPFTEVIRANIGDAQAMGQQPITFLRQVMALCTYPNLLDSPSFPEDAKKRARRILQACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVSGGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCDPKVLCIINPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKKVLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHPEIKGQLVKLLSVRLCPPVSGQAAMDIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCNPLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHFRMTILPPVEKLKTVLQKVKDFHINFLEKYA

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Horse
89
Bovine
89
Sheep
89
Pig
78
Rabbit
78
Xenopus
67
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q8TD30 基板として

Site PTM Type Enzyme
S25 Phosphorylation
R65 Methylation
T88 Phosphorylation
K406 Ubiquitination
Y491 Phosphorylation

研究背景

機能:

Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.

組織特異性:

Expressed at high levels in muscle, adipose tissue, kidney and brain and at lower levels in the liver and breast.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. Alanine aminotransferase subfamily.

研究領域

· Metabolism > Amino acid metabolism > Arginine biosynthesis.

· Metabolism > Amino acid metabolism > Alanine, aspartate and glutamate metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Metabolism > Global and overview maps > Carbon metabolism.

· Metabolism > Global and overview maps > 2-Oxocarboxylic acid metabolism.

· Metabolism > Global and overview maps > Biosynthesis of amino acids.

Restrictive clause

 

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For Research Use Only.
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