製品: MOGAT3 Antibody
カタログ: DF9099
タンパク質の説明: Rabbit polyclonal antibody to MOGAT3
アプリケーション: WB IHC IF/ICC
反応性: Human, Rat
予測: Dog
分子量: 39 kDa; 39kD(Calculated).
ユニプロット: Q86VF5
RRID: AB_2842295

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Dog(100%)
クローナリティ:
Polyclonal
特異性:
MOGAT3 Antibody detects endogenous levels of total MOGAT3.
RRID:
AB_2842295
引用形式: Affinity Biosciences Cat# DF9099, RRID:AB_2842295.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2 acylglycerol O acyltransferase 3; 2-acylglycerol O-acyltransferase 3; Acyl CoA:monoacylglycerol acyltransferase 3; Acyl coenzyme A:monoacylglycerol acyltransferase 3; Acyl-CoA:monoacylglycerol acyltransferase 3; DC 7; DC7; DGAT2L7; Diacylglycerol acyltransferase 2 like protein 7; Diacylglycerol acyltransferase 2-like protein 7; Diacylglycerol O acyltransferase candidate 7; Diacylglycerol O-acyltransferase candidate 7; hDC 7; hDC7; MGAT 3; MGAT3; MGC119203; MGC119204; MOGAT 3; MOGAT3; MOGT3_HUMAN; Monoacylglycerol O acyltransferase 3; Monoacylglycerol O-acyltransferase 3;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q86VF5 MOGT3_HUMAN:

Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.

タンパク質配列:
MGVATTLQPPTTSKTLQKQHLEAVGAYQYVLTFLFMGPFFSLLVFVLLFTSLWPFSVFYLVWLYVDWDTPNQGGRRSEWIRNRAIWRQLRDYYPVKLVKTAELPPDRNYVLGAHPHGIMCTGFLCNFSTESNGFSQLFPGLRPWLAVLAGLFYLPVYRDYIMSFGLCPVSRQSLDFILSQPQLGQAVVIMVGGAHEALYSVPGEHCLTLQKRKGFVRLALRHGASLVPVYSFGENDIFRLKAFATGSWQHWCQLTFKKLMGFSPCIFWGRGLFSATSWGLLPFAVPITTVVGRPIPVPQRLHPTEEEVNHYHALYMTALEQLFEEHKESCGVPASTCLTFI

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Pig
0
Horse
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Also able to catalyze the terminal step in triacylglycerol synthesis by using diacylglycerol and fatty acyl-CoA as substrates. Has a preference toward palmitoyl-CoA and oleoyl-CoA. May be involved in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes.

PTMs:

Ubiquitinated. Ubiquitination leads to proteasomal degradation.

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein. Cytoplasm>Perinuclear region.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Selectively expressed in the digestive system. Highly expressed in the ileum, and at lower level in jejunum, duodenum, colon, cecum and the rectum. Not expressed in the stomach and the esophagus and trachea. Expressed at very low level in liver.

タンパク質ファミリー:

Belongs to the diacylglycerol acyltransferase family.

研究領域

· Metabolism > Lipid metabolism > Glycerolipid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Digestive system > Fat digestion and absorption.

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