製品: ALPPL2 Antibody
カタログ: DF9033
タンパク質の説明: Rabbit polyclonal antibody to ALPPL2
アプリケーション: WB IHC IF/ICC
反応性: Human
分子量: 57 kDa; 57kD(Calculated).
ユニプロット: P10696
RRID: AB_2842229

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製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
ALPPL2 Antibody detects endogenous levels of total ALPPL2.
RRID:
AB_2842229
引用形式: Affinity Biosciences Cat# DF9033, RRID:AB_2842229.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Akp5; Alkaline phosphatase; Alkaline phosphatase Nagao isozyme; Alkaline phosphatase placental like; ALP 1; ALP-1; ALP1; ALPG; ALPPL 2; ALPPL; ALPPL2; C77216; D1Ertd816e; GCAP; Germ cell alkaline phosphatase; Nagao isozyme; Placental alkaline phosphatase-like; Placental like alkaline phosphatase; placental-like; PLAP like; PLAP-like; PPBN_HUMAN; Testicular and thymus alkaline phosphatase;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P10696 PPBN_HUMAN:

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

タンパク質配列:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP

PTMs - P10696 基板として

Site PTM Type Enzyme
K44 Ubiquitination
T50 Phosphorylation
K53 Ubiquitination
S111 Phosphorylation
T114 Phosphorylation
K123 Ubiquitination
K160 Ubiquitination
Y188 Phosphorylation
S196 Phosphorylation
Y225 Phosphorylation
T231 Phosphorylation
Y236 Phosphorylation
Y240 Phosphorylation
S241 Phosphorylation
K250 Ubiquitination
T364 Phosphorylation
S365 Phosphorylation
T369 Phosphorylation
T374 Phosphorylation
K400 Ubiquitination
K405 Ubiquitination
Y407 Phosphorylation
T408 Phosphorylation
Y412 Phosphorylation
Y418 Phosphorylation
K421 Ubiquitination
T429 Phosphorylation
S431 Phosphorylation
S433 Phosphorylation
S435 Phosphorylation
Y438 Phosphorylation

研究背景

細胞の位置付け:

Cell membrane>Lipid-anchor.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the alkaline phosphatase family.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > Thiamine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > Folate biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

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