FGF11 Antibody - #DF8944

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製品: FGF11 Antibody
カタログ: DF8944
タンパク質の説明: Rabbit polyclonal antibody to FGF11
アプリケーション: WB IHC
Cited expt.: WB
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 25 kDa(Observed); 25kD(Calculated).
ユニプロット: Q92914
RRID: AB_2842140

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#DF8944-BP

FGF11 Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse, Rat
予測:
Pig(100%), Bovine(%), Horse(%), Sheep(%), Rabbit(%), Dog(%)
クローナリティ:
Polyclonal
特異性:
FGF11 Antibody detects endogenous levels of total FGF11.
RRID:
AB_2842140
引用形式: Affinity Biosciences Cat# DF8944, RRID:AB_2842140.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

FGF 11; FGF-11; FGF11; FGF11_HUMAN; FHF 3; FHF-3; FHF3; Fibroblast growth factor 11; Fibroblast growth factor homologous factor 3; FLJ16061; MGC102953; MGC45269;

免疫原

免疫原:

A synthesized peptide derived from human FGF11, corresponding to a region within the internal amino acids.

Uniprot:

Q92914(FGF11_HUMAN) >>Visit HPA database.

遺伝子(ID):
FGF11(2256)
発現特異性:
Q92914 FGF11_HUMAN:

Nervous system.

タンパク質配列:
MAALASSLIRQKREVREPGGSRPVSAQRRVCPRGTKSLCQKQLLILLSKVRLCGGRPARPDRGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPEASPSSPPAP

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Rabbit
92
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Probably involved in nervous system development and function.

組織特異性:

Nervous system.

タンパク質ファミリー:

Belongs to the heparin-binding growth factors family.

参考文献

1). Circ_0004851 regulates the molecular mechanism of miR-296-3p/FGF11 in the influence of high iodine on PTC. Journal of translational medicine, 2024 (PubMed: 38902782) [IF=7.4]

Application: WB    Species: human    Sample: PTC tissues

Fig. 2 Construction of ceRNA network mediated by circRNA under iodine exposure. A. Volcano map. Red points represent up-regulated genes. Green points represent down-regulated genes. Blue points represent insignificant differentially expressed genes. B. Significant difference clustering heat map. Red color represents high gene expression in the sample, while green color represents low gene expression in the sample compared to the IN group. C. A total of 38 circRNA/miRNA/mRNA relationships were identified, including 7 miRNAs, 16 circRNAs and 13 mRNAs. D. Six ceRNA axes were identified for validation. the red indicates the up-regulated gene and the green indicates the down-regulated gene. E. Reverse transcription-quantitative PCR was used to detect the expression levels of 3 miRNAs, 3 circRNAs and 6 mRNAs in PTC tissues. F. The expression level of FGF11 protein was detected by Western blot in PTC tissues. G. PCR for circ_0004851、miR-296-3p、FGF11 in PTC cell. H. Western blot for FGF11 in PTC cell

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