| 製品: | CDCA7L Antibody |
| カタログ: | DF8916 |
| タンパク質の説明: | Rabbit polyclonal antibody to CDCA7L |
| アプリケーション: | WB IHC |
| 反応性: | Human |
| 予測: | Pig, Sheep |
| 分子量: | 52 kDa(Observed); 52kD(Calculated). |
| ユニプロット: | Q96GN5 |
| RRID: | AB_2842112 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8916, RRID:AB_2842112.
折りたたみ／展開
c Myc Interacting protein JPO2; CDCA7L; DKFZp762L0311; HR1; JPO2; Protein JPO2; R1; RAM2; Transcription Factor RAM2;
免疫原
A synthesized peptide derived from human CDCA7L, corresponding to a region within the internal amino acids.
- Q96GN5 CDA7L_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MELATRYQIPKEVADIFNAPSDDEEFVGFRDDVPMETLSSEESCDSFDSLESGKQQDVRFHSKYFTEELRRIFIEDTDSETEDFAGFTQSDLNGKTNPEVMVVESDLSDDGKASLVSEEEEDEEEDKATPRRSRSRRSSIGLRVAFQFPTKKLANKPDKNSSSEQLFSSARLQNEKKTILERKKDCRQVIQREDSTSESEDDSRDESQESSDALLKRTMNIKENKAMLAQLLAELNSMPDFFPVRTPTSASRKKTVRRAFSEGQITRRMNPTRSARPPEKFALENFTVSAAKFAEEFYSFRRRKTIGGKCREYRRRHRISSFRPVEDITEEDLENVAITVRDKIYDKVLGNTCHQCRQKTIDTKTVCRNQGCCGVRGQFCGPCLRNRYGEDVRSALLDPDWVCPPCRGICNCSYCRKRDGRCATGILIHLAKFYGYDNVKEYLESLQKELVEDN
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Plays a role in transcriptional regulation as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to the promoter. Plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. Involved in apoptotic signaling pathways; May act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.
Phosphorylation increases its interaction with PSIP1.
Cytoplasm. Nucleus.
Note: Associates with chromatin. Translocates from cytoplasm to nucleus under dexamethasone induction.
Ubiquitous. Overexpressed in medulloblastoma.
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