KCIP1 Antibody - #DF8880

製品: KCIP1 Antibody
カタログ: DF8880
タンパク質の説明: Rabbit polyclonal antibody to KCIP1
アプリケーション: WB
反応性: Human, Mouse, Rat
分子量: 26 kDa; 27kD(Calculated).
ユニプロット: Q9NZI2
RRID: AB_2842076

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WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
KCIP1 Antibody detects endogenous levels of total KCIP1.
RRID:
AB_2842076
引用形式: Affinity Biosciences Cat# DF8880, RRID:AB_2842076.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

A type potassium channel modulatory protein 1; A-type potassium channel modulatory protein 1; KChIP1; KCIP1_HUMAN; Kcnip1; Kv channel interacting protein 1; Kv channel-interacting protein 1; MGC9; MGC95; Potassium channel interacting protein 1; Potassium channel-interacting protein 1; VABP; Vesicle APC binding protein; Vesicle APC-binding protein;

免疫原

免疫原:

A synthesized peptide derived from human KCIP1, corresponding to a region within C-terminal amino acids.

Uniprot:

Q9NZI2(KCIP1_HUMAN) >>Visit HPA database.

遺伝子(ID):
KCNIP1(30820)
発現特異性:
Q9NZI2 KCIP1_HUMAN:

Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.

タンパク質配列:
MGAVMGTFSSLQTKQRRPSKDIAWWYYQYQRDKIEDELEMTMVCHRPEGLEQLEAQTNFTKRELQVLYRGFKNECPSGVVNEDTFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDNIMRSLQLFQNVM

研究背景

機能:

Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.

細胞の位置付け:

Cell membrane>Peripheral membrane protein. Cytoplasm. Cell projection>Dendrite.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Isoform 1 and isoform 2 are expressed in brain and kidney. Isoform 1 is also expressed in liver, pancreas, skeletal muscle, small intestine and testis. Isoform 2 is also expressed in lung, pancreas, leukocytes, prostate and thymus.

タンパク質ファミリー:

Belongs to the recoverin family.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.