製品: SPZ1 Antibody
カタログ: DF8866
タンパク質の説明: Rabbit polyclonal antibody to SPZ1
アプリケーション: WB IHC IF/ICC
反応性: Human, Rat
分子量: 50kD; 49kD(Calculated).
ユニプロット: Q9BXG8
RRID: AB_2842063

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Polyclonal
特異性:
SPZ1 Antibody detects endogenous levels of total SPZ1.
RRID:
AB_2842063
引用形式: Affinity Biosciences Cat# DF8866, RRID:AB_2842063.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

BHLH Zip transcription factor SPZ1; FLJ25709; MGC133987; NYD TSP1; PP1C gamma 2; PP1C gamma; PPP1R148; Protein phosphatase 1, regulatory subunit 148; Spermatogenic leucine zipper 1; Spermatogenic leucine zipper protein 1; Spermatogenic Zip 1; Spz1; Testis secretory sperm-binding protein Li 232m; Testis specific protein 1; Testis specific protein NYD TSP1; TSP1;

免疫原

免疫原:

A synthesized peptide derived from human SPZ1, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9BXG8 SPZ1_HUMAN:

Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.

タンパク質配列:
MASSAKSAEMPTISKTVNPTPDPHQEYLDPRITIALFEIGSHSPSSWGSLPFLKNSSHQVTEQQTAQKFNNLLKEIKDILKNMAGFEEKITEAKELFEETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQEMILETNITEDVSAHKENIRGLDKINEMLSTNLPVSLAPEKEDNEKKQQMIMENQNSENTAQVFARDLVNRLEEKKVLNETQQSQEKAKNRLNVQEETMKIRNNMEQLLQEAEHWSKQHTELSKLIKSYQKSQKDISETLGNNGVGFQTQPNNEVSAKHELEEQVKKLSHDTYSLQLMAALLENECQILQQRVEILKELHHQKQGTLQEKPIQINYKQDKKNQKPSEAKKVEMYKQNKQAMKGTFWKKDRSCRSLDVCLNKKACNTQFNIHVARKALRGKMRSASSLR

研究背景

機能:

Transcription factor that binds to the DNA sequence 5'-CANNTG-3'(E box) and the G-box motif. May play an important role in the regulation of cell proliferation and differentiation during spermatogenesis (By similarity).

PTMs:

Phosphorylated by MAPK1/ERK2 and MAPK3/ERK1.

細胞の位置付け:

Cytoplasm. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Specifically and strongly expressed in the testis. Expressed in several tumor cell lines.

Restrictive clause

 

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For Research Use Only.
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