SDCCAG8 Antibody - #DF8846
| 製品: | SDCCAG8 Antibody |
| カタログ: | DF8846 |
| タンパク質の説明: | Rabbit polyclonal antibody to SDCCAG8 |
| アプリケーション: | WB |
| 反応性: | Human, Mouse |
| 分子量: | 83 kDa(Observed); 83kD(Calculated). |
| ユニプロット: | Q86SQ7 |
| RRID: | AB_2842043 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8846, RRID:AB_2842043.
折りたたみ／展開
Antigen NY CO 8; Antigen NY-CO-8; BBS16; CCCAP; CCCAP SLSN7; Centrosomal colon cancer autoantigen protein; hCCCAP; HSPC085; NPHP10; NPHP10 gene; NY-CO-8; Sdccag8; SDCG8_HUMAN; Serologically defined colon cancer antigen 8; Serologically defined colon cancer antigen 8 homolog; SLSN7; SLSN7 gene;
免疫原
A synthesized peptide derived from human SDCCAG8, corresponding to a region within the internal amino acids.
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
- Q86SQ7 SDCG8_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAKSPENSTLEEILGQYQRSLREHASRSIHQLTCALKEGDVTIGEDAPNLSFSTSVGNEDARTAWPELQQSHAVNQLKDLLRQQADKESEVSPSRRRKMSPLRSLEHEETNMPTMHDLVHTINDQSQYIHHLEAEVKFCKEELSGMKNKIQVVVLENEGLQQQLKSQRQEETLREQTLLDASGNMHNSWITTGEDSGVGETSKRPFSHDNADFGKAASAGEQLELEKLKLTYEEKCEIEESQLKFLRNDLAEYQRTCEDLKEQLKHKEFLLAANTCNRVGGLCLKCAQHEAVLSQTHTNVHMQTIERLVKERDDLMSALVSVRSSLADTQQREASAYEQVKQVLQISEEANFEKTKALIQCDQLRKELERQAERLEKELASQQEKRAIEKDMMKKEITKEREYMGSKMLILSQNIAQLEAQVEKVTKEKISAINQLEEIQSQLASREMDVTKVCGEMRYQLNKTNMEKDEAEKEHREFRAKTNRDLEIKDQEIEKLRIELDESKQHLEQEQQKAALAREECLRLTELLGESEHQLHLTRQEKDSIQQSFSKEAKAQALQAQQREQELTQKIQQMEAQHDKTENEQYLLLTSQNTFLTKLKEECCTLAKKLEQISQKTRSEIAQLSQEKRYTYDKLGKLQRRNEELEEQCVQHGRVHETMKQRLRQLDKHSQATAQQLVQLLSKQNQLLLERQSLSEEVDRLRTQLPSMPQSDC
研究背景
Plays a role in the establishment of cell polarity and epithelial lumen formation (By similarity). Plays also an essential role in ciliogenesis and subsequent Hedgehog signaling pathway that requires the presence of intact primary cilia for pathway activation. Mechanistically, interacts with and mediates RABEP2 centrosomal localization which is critical for ciliogenesis.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome>Centriole. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Cytoplasm>Cytoskeleton>Cilium basal body. Cell junction.
Note: Located at the distal ends of both centrioles and colocalizes to centrosomes throughout the cell cycle.
Cytoplasm.
Expressed in thymus, prostate, testis, ovary, small intestine, colon, mucosa, colon and renal cancer tumors.
Restrictive clause
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