RFC3 Antibody - #DF8600
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8600, RRID:AB_2841804.
折りたたみ／展開
A1 38 kDa subunit; Activator 1 38 kDa subunit; Activator 1 subunit 3; HGNC:9971; MGC5276; Replication factor C (activator 1) 3; Replication factor C (activator 1) 3, 38kDa; Replication factor C 3; Replication factor C 38 kDa subunit; Replication factor C subunit 3; RF-C 38 kDa subunit; RFC 38 kD subunit; RFC 38 kDa subunit; RFC3; RFC3_HUMAN; RFC38;
免疫原
- P40938 RFC3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P40938 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| K7 | Methylation | Uniprot | |
| K7 | Ubiquitination | Uniprot | |
| S12 | Phosphorylation | Uniprot | |
| K20 | Acetylation | Uniprot | |
| K20 | Ubiquitination | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| Y60 | Phosphorylation | Uniprot | |
| K66 | Ubiquitination | Uniprot | |
| T75 | Phosphorylation | Uniprot | |
| T76 | Phosphorylation | Uniprot | |
| K79 | Ubiquitination | Uniprot | |
| Y91 | Phosphorylation | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| T123 | Phosphorylation | Uniprot | |
| S125 | Phosphorylation | Uniprot | |
| K130 | Ubiquitination | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| K142 | Ubiquitination | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| K170 | Ubiquitination | Uniprot | |
| K201 | Ubiquitination | Uniprot | |
| K202 | Ubiquitination | Uniprot | |
| S209 | Phosphorylation | Uniprot | |
| K218 | Ubiquitination | Uniprot | |
| K225 | Ubiquitination | Uniprot | |
| T283 | Phosphorylation | Uniprot | |
| Y343 | Phosphorylation | Uniprot |
研究背景
The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1.
Nucleus.
Heterotetramer of subunits RFC2, RFC3, RFC4 and RFC5 that can form a complex either with RFC1 or with RAD17. The former interacts with PCNA in the presence of ATP, while the latter has ATPase activity but is not stimulated by PCNA.
Belongs to the activator 1 small subunits family.
研究領域
· Genetic Information Processing > Replication and repair > DNA replication.
· Genetic Information Processing > Replication and repair > Nucleotide excision repair.
· Genetic Information Processing > Replication and repair > Mismatch repair.
Restrictive clause
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For Research Use Only.
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