製品: PANK2 Antibody
カタログ: DF8588
タンパク質の説明: Rabbit polyclonal antibody to PANK2
アプリケーション: WB IF/ICC
反応性: Human
分子量: 62 kDa; 63kD(Calculated).
ユニプロット: Q9BZ23
RRID: AB_2841792

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
PANK2 Antibody detects endogenous levels of total PANK2.
RRID:
AB_2841792
引用形式: Affinity Biosciences Cat# DF8588, RRID:AB_2841792.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

4933409I19Rik; AI642621; C20orf48; Hallervorden Spatz syndrome; HARP; hPANK2; HSS; MGC118448; MGC15053; mitochondrial; NBIA1; PANK2; PANK2_HUMAN; Pantothenate kinase 2 (Hallervorden Spatz syndrome); Pantothenate kinase 2; Pantothenate kinase 2 mitochondrial; Pantothenic acid kinase 2; PKAN; RP23 387C21.4;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9BZ23 PANK2_HUMAN:

Ubiquitous.

タンパク質配列:
MRRLGPFHPRVHWAAPPSLSSGLHRLLFLRGTRIPSSTTLSPPRHDSLSLDGGTVNPPRVREPTGREAFGPSPASSDWLPARWRNGRGGRPRARLCSGWTAAEEARRNPTLGGLLGRQRLLLRMGGGRLGAPMERHGRASATSVSSAGEQAAGDPEGRRQEPLRRRASSASVPAVGASAEGTRRDRLGSYSGPTSVSRQRVESLRKKRPLFPWFGLDIGGTLVKLVYFEPKDITAEEEEEEVESLKSIRKYLTSNVAYGSTGIRDVHLELKDLTLCGRKGNLHFIRFPTHDMPAFIQMGRDKNFSSLHTVFCATGGGAYKFEQDFLTIGDLQLCKLDELDCLIKGILYIDSVGFNGRSQCYYFENPADSEKCQKLPFDLKNPYPLLLVNIGSGVSILAVYSKDNYKRVTGTSLGGGTFFGLCCLLTGCTTFEEALEMASRGDSTKVDKLVRDIYGGDYERFGLPGWAVASSFGNMMSKEKREAVSKEDLARATLITITNNIGSIARMCALNENINQVVFVGNFLRINTIAMRLLAYALDYWSKGQLKALFSEHEGYFGAVGALLELLKIP

PTMs - Q9BZ23 基板として

Site PTM Type Enzyme
S140 Phosphorylation
T142 Phosphorylation
S143 Phosphorylation
S168 Phosphorylation
S169 Phosphorylation
S171 Phosphorylation
S189 Phosphorylation
Y190 Phosphorylation
S191 Phosphorylation
T194 Phosphorylation
S195 Phosphorylation
S203 Phosphorylation
K231 Ubiquitination
K246 Ubiquitination
K250 Ubiquitination
K271 Ubiquitination
K279 Ubiquitination
K371 Ubiquitination
S395 Phosphorylation
Y400 Phosphorylation
Y405 Phosphorylation
S470 Phosphorylation
S471 Phosphorylation
S477 Phosphorylation
K486 Ubiquitination
K543 Ubiquitination

研究背景

機能:

May be the master regulator of the CoA biosynthesis.

細胞の位置付け:

Mitochondrion.

Cytoplasm.

Cytoplasm.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the type II pantothenate kinase family.

研究領域

· Metabolism > Metabolism of cofactors and vitamins > Pantothenate and CoA biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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