ADM Antibody - #DF8501
(1)
Copy Info
| 製品: | ADM Antibody |
| カタログ: | DF8501 |
| タンパク質の説明: | Rabbit polyclonal antibody to ADM |
| アプリケーション: | WB |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 20 kDa(Observed); 20kD(Calculated). |
| ユニプロット: | P35318 |
| RRID: | AB_2841707 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8501, RRID:AB_2841707.
折りたたみ／展開
Adm; ADM precursor; ADML_HUMAN; AM; PAMP; Preproadrenomedullin; Proadrenomedullin N-20 terminal peptide; Proadrenomedullin N20 terminal peptide; ProAM N terminal 20 peptide; ProAM N-terminal 20 peptide; ProAM N20; ProAM-N20; ProAMN20;
免疫原
A synthesized peptide derived from human ADM, corresponding to a region within N-terminal amino acids.
Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
- P35318 ADML_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.
Secreted.
Highest levels found in pheochromocytoma and adrenal medulla. Also found in lung, ventricle and kidney tissues.
Belongs to the adrenomedullin family.
参考文献
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