製品: PCYOX1 Antibody
カタログ: DF8332
タンパク質の説明: Rabbit polyclonal antibody to PCYOX1
アプリケーション: WB
反応性: Human, Mouse, Rat
分子量: 57 kDa; 57kD(Calculated).
ユニプロット: Q9UHG3
RRID: AB_2841603

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
PCYOX1 Antibody detects endogenous levels of total PCYOX1.
RRID:
AB_2841603
引用形式: Affinity Biosciences Cat# DF8332, RRID:AB_2841603.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

EC 1.8.3.5; KIAA0908; PCL1; PCYOX_HUMAN; PCYOX1; Prenylcysteine lyase; Prenylcysteine oxidase 1; Prenylcysteine oxidase precursor;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9UHG3 PCYOX_HUMAN:

Ubiquitous.

タンパク質配列:
MGRVVAELVSSLLGLWLLLCSCGCPEGAELRAPPDKIAIIGAGIGGTSAAYYLRQKFGKDVKIDLFEREEVGGRLATMMVQGQEYEAGGSVIHPLNLHMKRFVKDLGLSAVQASGGLLGIYNGETLVFEESNWFIINVIKLVWRYGFQSLRMHMWVEDVLDKFMRIYRYQSHDYAFSSVEKLLHALGGDDFLGMLNRTLLETLQKAGFSEKFLNEMIAPVMRVNYGQSTDINAFVGAVSLSCSDSGLWAVEGGNKLVCSGLLQASKSNLISGSVMYIEEKTKTKYTGNPTKMYEVVYQIGTETRSDFYDIVLVATPLNRKMSNITFLNFDPPIEEFHQYYQHIVTTLVKGELNTSIFSSRPIDKFGLNTVLTTDNSDLFINSIGIVPSVREKEDPEPSTDGTYVWKIFSQETLTKAQILKLFLSYDYAVKKPWLAYPHYKPPEKCPSIILHDRLYYLNGIECAASAMEMSAIAAHNAALLAYHRWNGHTDMIDQDGLYEKLKTEL

PTMs - Q9UHG3 基板として

Site PTM Type Enzyme
T47 Phosphorylation
Y51 Phosphorylation
K62 Ubiquitination
K162 Ubiquitination
S171 Phosphorylation
Y174 Phosphorylation
S177 Phosphorylation
N196 N-Glycosylation
T202 Phosphorylation
K205 Ubiquitination
C258 S-Nitrosylation
Y308 Phosphorylation
N323 N-Glycosylation
Y339 Phosphorylation
N353 N-Glycosylation
K392 Ubiquitination
Y403 Phosphorylation
K415 Acetylation
K415 Ubiquitination
Y425 Phosphorylation
Y427 Phosphorylation
Y482 Phosphorylation
Y498 Phosphorylation

研究背景

機能:

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.

PTMs:

The protein is glycosylated at one or more potential N-glycosylation sites.

細胞の位置付け:

Lysosome.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

タンパク質ファミリー:

Belongs to the prenylcysteine oxidase family.

研究領域

· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.

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