MLLT11 Antibody - #DF8213
| 製品: | MLLT11 Antibody |
| カタログ: | DF8213 |
| タンパク質の説明: | Rabbit polyclonal antibody to MLLT11 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 10 kDa; 10kD(Calculated). |
| ユニプロット: | Q13015 |
| RRID: | AB_2841518 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF8213, RRID:AB_2841518.
折りたたみ／展開
AF1Q; AF1Q_HUMAN; ALL1 fused gene from chromosome 1q; MLLT 11; MLLT11; Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila) translocated to 11; Protein AF1q; RP11 316M1.10;
免疫原
A synthesized peptide derived from human MLLT11, corresponding to a region within N-terminal amino acids.
Expressed in myoepithelial cells of normal breast tissue (at protein level) (PubMed:26079538). Highly expressed in thymus (PubMed:7833468). Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen (PubMed:7833468).
- Q13015 AF1Q_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRDPVSSQYSSFLFWRMPIPELDLSELEGLGLSDTATYKVKDSSVGKMIGQATAADQEKNPEGDGLLEYSTFNFWRAPIASIHSFELDLL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Cofactor for the transcription factor TCF7. Involved in regulation of lymphoid development by driving multipotent hematopoietic progenitor cells towards a T cell fate.
Ubiquitinated, leading to degradation.
Nucleus. Cytoplasm. Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
Note: Continuous nuclear export is followed by degradation.
Expressed in myoepithelial cells of normal breast tissue (at protein level). Highly expressed in thymus. Expressed in colon, small intestine, prostate and ovary. Not detected in peripheral blood lymphocytes and spleen.
Belongs to the MLLT11 family.
Restrictive clause
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For Research Use Only.
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