製品: PTRH2 Antibody
カタログ: DF8201
タンパク質の説明: Rabbit polyclonal antibody to PTRH2
アプリケーション: WB
反応性: Human, Mouse
分子量: 19 kDa(Observed); 19kD(Calculated).
ユニプロット: Q9Y3E5
RRID: AB_2841509

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
PTRH2 Antibody detects endogenous levels of total PTRH2.
RRID:
AB_2841509
引用形式: Affinity Biosciences Cat# DF8201, RRID:AB_2841509.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Bcl 2 inhibitor of transcription 1; Bcl-2 inhibitor of transcription 1; BIT 1; BIT1; CGI 147; CGI147; mitochondrial; Peptidyl tRNA hydrolase 2 mitochondrial; Peptidyl-tRNA hydrolase 2; PTH 2; PTH2; PTH2_HUMAN; PTRH 2; PTRH2;

免疫原

免疫原:

A synthesized peptide derived from human PTRH2, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
タンパク質配列:
MPSKSLVMEYLAHPSTLGLAVGVACGMCLGWSLRVCFGMLPKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY

研究背景

機能:

The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.

Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.

PTMs:

Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.

細胞の位置付け:

Mitochondrion.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the PTH2 family.

Restrictive clause

 

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Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.