PTRH2 Antibody - #DF8201
| 製品: | PTRH2 Antibody |
| カタログ: | DF8201 |
| タンパク質の説明: | Rabbit polyclonal antibody to PTRH2 |
| アプリケーション: | |
| 反応性: | Human, Mouse |
| 分子量: | 19 kDa(Observed); 19kD(Calculated). |
| ユニプロット: | Q9Y3E5 |
| RRID: | AB_2841509 |
Control Products
製品説明
ソース:
Rabbit
反応性:
Human, Mouse
クローナリティ:
Polyclonal
特異性:
PTRH2 Antibody detects endogenous levels of total PTRH2.
RRID:
AB_2841509
引用形式: Affinity Biosciences Cat# DF8201, RRID:AB_2841509.
引用形式: Affinity Biosciences Cat# DF8201, RRID:AB_2841509.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ/展開
Bcl 2 inhibitor of transcription 1; Bcl-2 inhibitor of transcription 1; BIT 1; BIT1; CGI 147; CGI147; mitochondrial; Peptidyl tRNA hydrolase 2 mitochondrial; Peptidyl-tRNA hydrolase 2; PTH 2; PTH2; PTH2_HUMAN; PTRH 2; PTRH2;
免疫原
免疫原:
A synthesized peptide derived from human PTRH2, corresponding to a region within the internal amino acids.
Uniprot:
遺伝子(ID):
タンパク質配列:
- Q9Y3E5 PTH2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPSKSLVMEYLAHPSTLGLAVGVACGMCLGWSLRVCFGMLPKSKTSKTHTDTESEASILGDSGEYKMILVVRNDLKMGKGKVAAQCSHAAVSAYKQIQRRNPEMLKQWEYCGQPKVVVKAPDEETLIALLAHAKMLGLTVSLIQDAGRTQIAPGSQTVLGIGPGPADLIDKVTGHLKLY
研究背景
機能:
The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.
PTMs:
Ubiquitinated by PRKN during mitophagy, leading to its degradation and enhancement of mitophagy. Deubiquitinated by USP30.
細胞の位置付け:
Mitochondrion.
タンパク質ファミリー:
Belongs to the PTH2 family.
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