製品: CTNNBL1 Antibody
カタログ: DF7835
タンパク質の説明: Rabbit polyclonal antibody to CTNNBL1
アプリケーション: WB IHC IF/ICC
反応性: Human
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken
分子量: 65 kDa; 65kD(Calculated).
ユニプロット: Q8WYA6
RRID: AB_2841275

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Rabbit(100%), Dog(100%), Chicken(100%)
クローナリティ:
Polyclonal
特異性:
CTNNBL1 Antibody detects endogenous levels of total CTNNBL1.
RRID:
AB_2841275
引用形式: Affinity Biosciences Cat# DF7835, RRID:AB_2841275.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

5730471K09Rik; Beta catenin like 1; Beta catenin like protein 1; Beta-catenin-like protein 1; C20orf33; Cadherin associated protein; Catenin beta like 1; Chromosome 20 open reading frame 3; CTBL1_HUMAN; CTNN protein; CTNNBL 1; Ctnnbl1; dJ633O20.1; FLJ21108; NAP; Nuclear associated protein; nuclear protein NAP; Nuclear-associated protein; NYD SP19; OTTMUSP00000016933; P14; P14L; PP8304; RP5 1118M15.1; Testis development protein NYD SP19; Testis development protein NYD-SP19;

免疫原

免疫原:

A synthesized peptide derived from human CTNNBL1, corresponding to a region within N-terminal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q8WYA6 CTBL1_HUMAN:

Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.

タンパク質配列:
MDVGELLSYQPNRGTKRPRDDEEEEQKMRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLRGQQRTRLLNKFTENDSEKVDRLMELHFKYLGAMQVADKKIEGEKHDMVRRGEIIDNDTEEEFYLRRLDAGLFVLQHICYIMAEICNANVPQIRQRVHQILNMRGSSIKIVRHIIKEYAENIGDGRSPEFRENEQKRILGLLENF

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Rabbit
100
Xenopus
75
Zebrafish
75
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.

細胞の位置付け:

Nucleus.

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid.

タンパク質ファミリー:

The surface residues of the concave side of the superhelical ARM repeat region contribute to, but are not essential for NLS binding.

研究領域

· Genetic Information Processing > Transcription > Spliceosome.

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