製品: HNRNPUL1 Antibody
カタログ: DF7810
タンパク質の説明: Rabbit polyclonal antibody to HNRNPUL1
アプリケーション: WB IF/ICC
反応性: Human, Rat
予測: Pig, Bovine, Horse, Rabbit, Dog, Xenopus
分子量: 96 kDa; 96kD(Calculated).
ユニプロット: Q9BUJ2
RRID: AB_2841262

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
予測:
Pig(100%), Bovine(92%), Horse(100%), Rabbit(100%), Dog(100%), Xenopus(80%)
クローナリティ:
Polyclonal
特異性:
HNRNPUL1 Antibody detects endogenous levels of total HNRNPUL1.
RRID:
AB_2841262
引用形式: Affinity Biosciences Cat# DF7810, RRID:AB_2841262.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Adenovirus early region 1B associated protein 5; Adenovirus early region 1B-associated protein 5; E130317O14Rik; E1B 55 kDa associated protein 5; E1B AP5; E1B-55 kDa-associated protein 5; E1B-AP5; E1BAP5; fb53d10; fk45c03; FLJ12944; Heterogeneous nuclear ribonucleoprotein U-like protein 1; HNRL1_HUMAN; Hnrnpul1; HNRPUL1; MGC36621; MGC78330; wu:fb53d10; wu:fk45c03; zgc:85971;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MDVRRLKVNELREELQRRGLDTRGLKAELAERLQAALEAEEPDDERELDADDEPGRPGHINEEVETEGGSELEGTAQPPPPGLQPHAEPGGYSGPDGHYAMDNITRQNQFYDTQVIKQENESGYERRPLEMEQQQAYRPEMKTEMKQGAPTSFLPPEASQLKPDRQQFQSRKRPYEENRGRGYFEHREDRRGRSPQPPAEEDEDDFDDTLVAIDTYNCDLHFKVARDRSSGYPLTIEGFAYLWSGARASYGVRRGRVCFEMKINEEISVKHLPSTEPDPHVVRIGWSLDSCSTQLGEEPFSYGYGGTGKKSTNSRFENYGDKFAENDVIGCFADFECGNDVELSFTKNGKWMGIAFRIQKEALGGQALYPHVLVKNCAVEFNFGQRAEPYCSVLPGFTFIQHLPLSERIRGTVGPKSKAECEILMMVGLPAAGKTTWAIKHAASNPSKKYNILGTNAIMDKMRVMGLRRQRNYAGRWDVLIQQATQCLNRLIQIAARKKRNYILDQTNVYGSAQRRKMRPFEGFQRKAIVICPTDEDLKDRTIKRTDEEGKDVPDHAVLEMKANFTLPDVGDFLDEVLFIELQREEADKLVRQYNEEGRKAGPPPEKRFDNRGGGGFRGRGGGGGFQRYENRGPPGGNRGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPPQQPPPPQPPPQQPPPPPSYSPARNPPGASTYNKNSNIPGSSANTSTPTVSSYSPPQPSYSQPPYNQGGYSQGYTAPPPPPPPPPAYNYGSYGGYNPAPYTPPPPPTAQTYPQPSYNQYQQYAQQWNQYYQNQGQWPPYYGNYDYGSYSGNTQGGTSTQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Dog
100
Rabbit
100
Bovine
92
Xenopus
80
Zebrafish
67
Sheep
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BUJ2 基板として

Site PTM Type Enzyme
R23 Methylation
K26 Ubiquitination
Y111 Phosphorylation
K117 Sumoylation
K117 Ubiquitination
Y124 Phosphorylation
Y137 Phosphorylation
K142 Sumoylation
K142 Ubiquitination
K146 Sumoylation
K146 Ubiquitination
T151 Phosphorylation
S152 Phosphorylation
S159 Phosphorylation
K162 Acetylation
K162 Ubiquitination
K172 Methylation
K172 Ubiquitination
Y175 Phosphorylation
R179 Methylation
R181 Methylation
Y183 Phosphorylation
S194 Phosphorylation
T209 Phosphorylation
T215 Phosphorylation
K270 Acetylation
K270 Ubiquitination
K309 Ubiquitination
K310 Ubiquitination
K350 Ubiquitination
C377 S-Nitrosylation
K418 Ubiquitination
K440 Acetylation
K440 Methylation
K440 Sumoylation
K440 Ubiquitination
S444 Phosphorylation
K449 Sumoylation
K449 Ubiquitination
Y450 Phosphorylation
T455 Phosphorylation
K461 Ubiquitination
C487 S-Nitrosylation
Y510 Phosphorylation
S512 Phosphorylation
K517 Ubiquitination
K527 Sumoylation
K527 Ubiquitination
C532 S-Nitrosylation
K539 Sumoylation
K539 Ubiquitination
R584 Methylation
R592 Methylation
K600 Ubiquitination
R612 Methylation
R618 Methylation
R620 Methylation
R628 Methylation
R632 Methylation
R639 Methylation
R645 Methylation
S649 Phosphorylation
R656 Methylation
R661 Methylation
S668 Phosphorylation
R671 Methylation
R685 Methylation
S687 Phosphorylation
R690 Methylation
S716 Phosphorylation P24941 (CDK2)
Y717 Phosphorylation
S718 Phosphorylation P24941 (CDK2)

研究背景

機能:

Acts as a basic transcriptional regulator. Represses basic transcription driven by several virus and cellular promoters. When associated with BRD7, activates transcription of glucocorticoid-responsive promoter in the absence of ligand-stimulation. Plays also a role in mRNA processing and transport. Binds avidly to poly(G) and poly(C) RNA homopolymers in vitro.

PTMs:

Methylated.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with the adenovirus type 5 (Ad5) E1B-55 kDa, BRD7, PRMT2, TP53 and NXF1. Associates with histones and BRD7.

タンパク質ファミリー:

The RGG-box domain is methylated.

研究領域

· Human Diseases > Infectious diseases: Viral > Influenza A.

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