DIRA1 Antibody - #AF0516

(1)  
製品: DIRA1 Antibody
カタログ: AF0516
タンパク質の説明: Rabbit polyclonal antibody to DIRA1
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Dog
分子量: 22kDa; 22kD(Calculated).
ユニプロット: O95057
RRID: AB_2834402

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(82%), Bovine(82%), Horse(82%), Sheep(82%), Dog(82%)
クローナリティ:
Polyclonal
特異性:
DIRA1 Antibody detects endogenous levels of total DIRA1.
RRID:
AB_2834402
引用形式: Affinity Biosciences Cat# AF0516, RRID:AB_2834402.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Di Ras1; DIRAS family GTP binding RAS like 1; Distinct subgroup of the Ras family member 1; FLJ42681; GBTS1; GTP binding protein Di Ras1; Ras related inhibitor of cell growth; RIG; Rig protein; Small GTP binding tumor suppressor 1;

免疫原

免疫原:

A synthesized peptide derived from human DIRA1, corresponding to a region within C-terminal amino acids.

Uniprot:

O95057(DIRA1_HUMAN) >>Visit HPA database.

遺伝子(ID):
DIRAS1(148252)
発現特異性:
O95057 DIRA1_HUMAN:

Highly expressed in heart and brain.

タンパク質の説明:
DIRAS1 Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family. Note: This description may include information from UniProtKB.
タンパク質配列:
MPEQSNDYRVVVFGAGGVGKSSLVLRFVKGTFRDTYIPTIEDTYRQVISCDKSVCTLQITDTTGSHQFPAMQRLSISKGHAFILVFSVTSKQSLEELGPIYKLIVQIKGSVEDIPVMLVGNKCDETQREVDTREAQAVAQEWKCAFMETSAKMNYNVKELFQELLTLETRRNMSLNIDGKRSGKQKRTDRVKGKCTLM

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
82
Horse
82
Bovine
82
Sheep
82
Dog
82
Chicken
73
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Displays low GTPase activity and exists predominantly in the GTP-bound form.

細胞の位置付け:

Cell membrane>Lipid-anchor>Cytoplasmic side.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in heart and brain.

タンパク質ファミリー:

Belongs to the small GTPase superfamily. Di-Ras family.

Restrictive clause

 

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