PDI Antibody - #DF7593
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| 製品: | PDI Antibody |
| カタログ: | DF7593 |
| タンパク質の説明: | Rabbit polyclonal antibody to PDI |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 分子量: | 61 kDa; 58kD(Calculated). |
| ユニプロット: | Q13087 |
| RRID: | AB_2841084 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7593, RRID:AB_2841084.
折りたたみ／展開
Pancreas-specific protein disulfide isomerase; pancreatic protein disulfide isomerase; PDIA2; PDIA2_HUMAN; PDIp; PDIR; protein disulfide isomerase family A member 2; protein disulfide isomerase, pancreatic; protein disulfide isomerase-associated 2; Protein disulfide-isomerase A2; Rho GDP dissociation inhibitor gamma;
免疫原
A synthesized peptide derived from human PDI, corresponding to a region within C-terminal amino acids.
- Q13087 PDIA2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSRQLLPVLLLLLLRASCPWGQEQGARSPSEEPPEEEIPKEDGILVLSRHTLGLALREHPALLVEFYAPWCGHCQALAPEYSKAAAVLAAESMVVTLAKVDGPAQRELAEEFGVTEYPTLKFFRNGNRTHPEEYTGPRDAEGIAEWLRRRVGPSAMRLEDEAAAQALIGGRDLVVIGFFQDLQDEDVATFLALAQDALDMTFGLTDRPRLFQQFGLTKDTVVLFKKFDEGRADFPVDEELGLDLGDLSRFLVTHSMRLVTEFNSQTSAKIFAARILNHLLLFVNQTLAAHRELLAGFGEAAPRFRGQVLFVVVDVAADNEHVLQYFGLKAEAAPTLRLVNLETTKKYAPVDGGPVTAASITAFCHAVLNGQVKPYLLSQEIPPDWDQRPVKTLVGKNFEQVAFDETKNVFVKFYAPWCTHCKEMAPAWEALAEKYQDHEDIIIAELDATANELDAFAVHGFPTLKYFPAGPGRKVIEYKSTRDLETFSKFLDNGGVLPTEEPPEEPAAPFPEPPANSTMGSKEEL
研究背景
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins.
The disulfide-linked homodimer exhibits an enhanced chaperone activity.
Glycosylated.
Endoplasmic reticulum lumen.
Highly expressed in pancreas (at protein level).
Belongs to the protein disulfide isomerase family.
参考文献
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