CD69 Antibody - #AF0624

製品: CD69 Antibody
カタログ: AF0624
タンパク質の説明: Rabbit polyclonal antibody to CD69
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Sheep, Dog
分子量: 23~40kD; 23kD(Calculated).
ユニプロット: Q07108
RRID: AB_2834386

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関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Sheep(86%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
CD69 Antibody detects endogenous levels of total CD69.
RRID:
AB_2834386
引用形式: Affinity Biosciences Cat# AF0624, RRID:AB_2834386.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Activation inducer molecule (AIM/CD69); Activation inducer molecule; AIM; BL-AC/P26; BLAC/P26; C-type lectin domain family 2 member C; CD69; CD69 antigen (p60, early T-cell activation antigen); CD69 antigen; CD69 molecule; CD69_HUMAN; CLEC2C; EA1; Early activation antigen CD69; Early lymphocyte activation antigen; Early T cell activation antigen p60; Early T-cell activation antigen p60; GP32/28; Leu23; Leukocyte surface antigen Leu-23; MLR-3; MLR3; VEA; Very Early Activation Antigen;

免疫原

免疫原:

A synthesized peptide derived from human CD69, corresponding to a region within the internal amino acids.

Uniprot:

Q07108(CD69_HUMAN) >>Visit HPA database.

遺伝子(ID):
CD69(969)
発現特異性:
Q07108 CD69_HUMAN:

Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

タンパク質の説明:
CD69 Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets. Induced by antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.
タンパク質配列:
MSSENCFVAENSSLHPESGQENDATSPHFSTRHEGSFQVPVLCAVMNVVFITILIIALIALSVGQYNCPGQYTFSMPSDSHVSSCSEDWVGYQRKCYFISTVKRSWTSAQNACSEHGATLAVIDSEKDMNFLKRYAGREEHWVGLKKEPGHPWKWSNGKEFNNWFNVTGSDKCVFLKNTEVSSMECEKNLYWICNKPYK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
88
Sheep
86
Bovine
75
Rabbit
71
Pig
63
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

PTMs:

Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.

細胞の位置付け:

Membrane>Single-pass type II membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.