TAS1R1 Antibody - #DF10278

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製品: TAS1R1 Antibody
カタログ: DF10278
タンパク質の説明: Rabbit polyclonal antibody to TAS1R1
アプリケーション: WB
Cited expt.: WB
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Dog, Chicken
分子量: 93kDa; 93kD(Calculated).
ユニプロット: Q7RTX1
RRID: AB_2840856

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MS Report
HPLC Report
MSDS
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WB Handbook
IHC Protocol
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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(88%), Bovine(88%), Horse(88%), Sheep(88%), Dog(88%), Chicken(88%)
クローナリティ:
Polyclonal
特異性:
TAS1R1 Antibody detects endogenous levels of total TAS1R1.
RRID:
AB_2840856
引用形式: Affinity Biosciences Cat# DF10278, RRID:AB_2840856.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

G protein coupled receptor 70; G protein-coupled receptor 70; G-protein coupled receptor 70; gm 148; gm148; GPR 70; GPR70; Krueppel related zinc finger protein 3 (HKR3 protein); seven transmembrane helix receptor; Sweet taste receptor T1r; T1R1; TAS1 R1; TAS1R1; Taste receptor type 1 member 1; taste receptor, type 1, member 1; TR 1; TR1; TS1R1_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from human TAS1R1, corresponding to a region within the internal amino acids.

Uniprot:

Q7RTX1(TS1R1_HUMAN) >>Visit HPA database.

遺伝子(ID):
TAS1R1(80835)
タンパク質配列:
MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLFPLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQLYDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLSPFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSDDYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERMQCLMRHLAQAGATVVVVFSSRQLARVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMVLGVAIQKRAVPGLKAFEEAYARADKKAPRPCHKGSWCSSNQLCRECQAFMAHTMPKLKAFSMSSAYNAYRAVYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYNIIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRVVTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHTSWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFGEPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLFVMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSISAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLSSLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
88
Horse
88
Bovine
88
Sheep
88
Dog
88
Chicken
88
Rabbit
75
Zebrafish
63
Xenopus
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the G-protein coupled receptor 3 family. TAS1R subfamily.

研究領域

· Organismal Systems > Sensory system > Taste transduction.

参考文献

1). Longitudinal Expression of Testicular TAS1R3 from Prepuberty to Sexual Maturity in Congjiang Xiang Pigs. Animals, 2021 (PubMed: 33567555) [IF=2.7]

Application: WB    Species: Pigs    Sample:

Figure 8 Transcription changes of umami tasting molecules, TAS1R1, TAS1R3 and PLCB2 during testis development of the Congjiang Xiang pig, evidenced by q-PCR. Gel electrophoresis q-PCR result of TAS1R1 (167 bp), TA1SR3 (235 bp), and PLCB2 (239 bp), respectively. The mRNA levels of target genes were normalized with housekeeping gene (ATCB, 61 bp) and expressed as 2−ΔΔCT using samples on day 30 as calibrator. Results are indicated by means ± SD (n = 3). Values not sharing the same letter (a, b) denote significant differences among groups (p < 0.05).

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