CXCL17 Antibody - #DF10167
| 製品: | CXCL17 Antibody |
| カタログ: | DF10167 |
| タンパク質の説明: | Rabbit polyclonal antibody to CXCL17 |
| アプリケーション: | WB |
| 反応性: | Human |
| 予測: | Bovine, Horse, Rabbit, Dog |
| 分子量: | 14 kDa(Observed); 14kD(Calculated). |
| ユニプロット: | Q6UXB2 |
| RRID: | AB_2840746 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF10167, RRID:AB_2840746.
免疫原
A synthesized peptide derived from human CXCL17, corresponding to a region within the internal amino acids.
Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation.
- Q6UXB2 CXL17_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKVLISSLLLLLPLMLMSMVSSSLNPGVARGHRDRGQASRRWLQEGGQECECKDWFLRAPRRKFMTVSGLPKKQCPCDHFKGNVKKTRHQRHHRKPNKHSRACQQFLKQCQLRSFALPL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Chemokine that acts as chemoattractant for monocytes, macrophages and dendritic cells. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach. May play a role in the innate defense against infections. Activates the C-X-C chemokine receptor GPR35 to induce a rapid and transient rise in the level of intracellular calcium ions.
seems exhibit much higher chemoattractant potency on monocytes and macrophages than 6-Cys CXCL17.
Likely to undergo an endoproteolytic process to form a four-cysteine-containing mature peptide with a canonical CXC chemokine scaffold after secretion.
Secreted.
Detected in trachea, stomach, lung and skeletal muscle. Detected in intestine and in normal and asthmatic lung (at protein level). Breast tumors showed 3- to 24-fold up-regulation.
Belongs to the intercrine alpha (chemokine CxC) family.
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