製品: ATP6V1G3 Antibody
カタログ: DF10005
タンパク質の説明: Rabbit polyclonal antibody to ATP6V1G3
アプリケーション: WB
反応性: Human
予測: Horse, Rabbit, Dog
分子量: 14 kDa; 14kD(Calculated).
ユニプロット: Q96LB4
RRID: AB_2840585

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:1000-3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Horse(88%), Rabbit(100%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
ATP6V1G3 Antibody detects endogenous levels of total ATP6V1G3.
RRID:
AB_2840585
引用形式: Affinity Biosciences Cat# DF10005, RRID:AB_2840585.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ATP6G3; atp6v1g3; ATPase, H+ transporting, lysosomal (vacuolar proton pump) subunit G3; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3; MGC119810; MGC119813; MGC130213; MGC130214; V ATPase 13 kDa subunit 3; V ATPase G subunit 3; V ATPase G3 subunit; V ATPase subunit G 3; V-ATPase 13 kDa subunit 3; V-ATPase subunit G 3; V-type proton ATPase subunit G 3; Vacuolar ATP synthase subunit G 3; Vacuolar proton pump G subunit 3; Vacuolar proton pump subunit G 3; Vacuolar proton pump, subunit G3; VATG3_HUMAN; Vma10;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質配列:
MTSQSQGIHQLLQAEKRAKDKLEEAKKRKGKRLKQAKEEAMVEIDQYRMQRDKEFRLKQSKIMGSQNNLSDEIEEQTLGKIQELNGHYNKYMESVMNQLLSMVCDMKPEIHVNYRATN

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Rabbit
100
Horse
88
Dog
88
Pig
0
Bovine
0
Sheep
0
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q96LB4 基板として

Site PTM Type Enzyme
K31 Acetylation
K37 Acetylation
K37 Ubiquitination

研究背景

機能:

Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.

組織特異性:

Kidney.

サブユニット構造:

V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (components: a, c, c', c'' and d).

タンパク質ファミリー:

Belongs to the V-ATPase G subunit family.

研究領域

· Cellular Processes > Transport and catabolism > Phagosome.   (View pathway)

· Environmental Information Processing > Signal transduction > mTOR signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Vibrio cholerae infection.

· Human Diseases > Infectious diseases: Bacterial > Epithelial cell signaling in Helicobacter pylori infection.

· Human Diseases > Immune diseases > Rheumatoid arthritis.

· Metabolism > Energy metabolism > Oxidative phosphorylation.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Nervous system > Synaptic vesicle cycle.

· Organismal Systems > Excretory system > Collecting duct acid secretion.

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