ECRG4 Antibody - #AF0475
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0475, RRID:AB_2834335.
折りたたみ／展開
AUGN_HUMAN; Augurin; C2orf40; Esophageal cancer-related gene 4 protein;
免疫原
A synthesized peptide derived from human ECRG4, corresponding to a region within C-terminal amino acids.
Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level).
- Q9H1Z8 AUGN_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREAPVPTKTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFRHGASVNYDDY
研究背景
Probable hormone that may attenuate cell proliferation and induce senescence of oligodendrocyte and neural precursor cells in the central nervous system (By similarity). ECRG4-induced senescence is characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation (By similarity).
Secreted. Cytoplasm. Apical cell membrane.
Expressed in the brain, with expression in the epithelial cell layer of the choroid plexus (at protein level).
Belongs to the augurin family.
Restrictive clause
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